Department of Clinical Oncology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China; Medical College, University of South China, Hengyang, China.
Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China; Department of Clinical Oncology, Queen Mary Hospital, Hong Kong, China; Department of Clinical Oncology, Tuen Mun Hospital, Hong Kong, China.
Chin Clin Oncol. 2021 Feb;10(1):9. doi: 10.21037/cco-20-89. Epub 2020 Jun 11.
Primary liver cancer includes hepatocellular carcinoma (HCC, 75-85%) and intrahepatic cholangiocarcinoma (10-15%). The vast majority of patients with primary HCC are not candidates for surgical treatment. Surgical resection, liver transplantation and percutaneous puncture are effective potentially curable treatments for patients with early stage liver cancer. Radiation therapy is a non-surgical alternative treatment that has generally been used to treat patients with advanced liver cancer, although it's use in the potentially curative setting is increasing. Radiotherapy is a non-invasive local treatment which works through ionizing radiation. This review summarizes the efficacy and safety of commonly used radiotherapy methods, and reviews three-dimensional conformal radiotherapy (3DCRT), intensity modulated radiation therapy (IMRT), stereotactic body radiotherapy (SBRT), volume-modulated arc therapy (VMAT), and internal radiation therapies, for primary liver cancer (in particular for HCC).
原发性肝癌包括肝细胞癌（HCC，占 75-85%）和肝内胆管癌（10-15%）。绝大多数原发性肝癌患者不符合手术治疗的条件。手术切除、肝移植和经皮穿刺是治疗早期肝癌患者的有效潜在治愈方法。放射治疗是一种非手术替代治疗方法，通常用于治疗晚期肝癌患者，尽管它在潜在可治愈的情况下的应用正在增加。放射治疗是一种非侵入性的局部治疗方法，通过电离辐射起作用。这篇综述总结了常用放射治疗方法的疗效和安全性，并回顾了三维适形放疗（3DCRT）、调强放疗（IMRT）、立体定向体部放疗（SBRT）、容积旋转调强放疗（VMAT）和内放射治疗，用于原发性肝癌（特别是 HCC）。
