确定中国2型糖尿病患者肥胖的体重指数和腰围最佳切点
Optimal Cut-Offs of Body Mass Index and Waist Circumference to Identify Obesity in Chinese Type 2 Diabetic Patients.
作者信息
Zhao Qinying, Chen Xiangjun, Wu Jinshan, Gong Lilin, Hu Jinbo, Yang Shumin, Li Qifu, Wang Zhihong
机构信息
Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
出版信息
Diabetes Metab Syndr Obes. 2020 Jun 3;13:1899-1909. doi: 10.2147/DMSO.S251574. eCollection 2020.
PURPOSE
The prevalence of general obesity (commonly defined by body mass index (BMI) in kg/m) and abdominal obesity (commonly assessed by waist circumference (WC)) has increased rapidly in China. The aim of this study was to investigate the diagnostic accuracy of traditional cut-offs for BMI or WC to identify general or abdominal obesity in Chinese type 2 diabetic patients and propose optimal cut-offs.
PATIENTS AND METHODS
BMI and WC were obtained from 1539 type 2 diabetic patients. Body fat percentage and visceral fat area measured by dual-energy x-ray absorptiometry were set as the gold standard to identify general and abdominal obesity. We assessed the diagnostic power of traditional cut-offs for BMI and WC to define obesity, and analyzed receive operating characteristic (ROC) curves to obtain the optimal cut-offs to identify obesity in Chinese type 2 diabetic patients.
RESULTS
In Chinese type 2 diabetic patients, the optimal BMI was 25 kg/m with the best trade-off between sensitivity and specificity (men: 74.6% (95% CI: 70.7-78.2%) and 65.1% (95% CI: 59.7-70.3%), AUC 0.78 (95% CI: 0.75-0.81), <0.05; women: 65.8% (95% CI: 60.3-71.0%) and 80.3% (95% CI: 75.7-84.3%), AUC 0.80 (95% CI: 0.77-0.83), <0.05) in both genders. The optimal WC was 93 cm in men and 90 cm in women with the best trade-off between sensitivity and specificity (men: 87.2% (95% CI: 84.3-89.8%) and 80.2% (95% CI: 74.9-84.8%), AUC 0.91 (95% CI: 0.88-0.92), <0.05; women: 81.0% (95% CI: 76.9-84.6%) and 88.7% (95% CI: 83.9-92.4%), AUC 0.92 (95% CI: 0.90-0.94), <0.05).
CONCLUSION
For the Chinese patients with type 2 diabetes, the optimal cut-offs for BMI or WC to identify general or abdominal obesity need to be reconsidered.
目的
中国总体肥胖（通常以体重指数（BMI，单位：kg/m²）定义）和腹型肥胖（通常通过腰围（WC）评估）的患病率迅速上升。本研究旨在调查BMI或WC的传统切点对中国2型糖尿病患者总体肥胖或腹型肥胖的诊断准确性，并提出最佳切点。
患者与方法
获取了1539例2型糖尿病患者的BMI和WC。将通过双能X线吸收法测量的体脂百分比和内脏脂肪面积作为识别总体肥胖和腹型肥胖的金标准。我们评估了BMI和WC的传统切点定义肥胖的诊断效能，并分析了受试者工作特征（ROC）曲线以获得中国2型糖尿病患者识别肥胖的最佳切点。
结果
在中国2型糖尿病患者中，最佳BMI为25 kg/m²，在敏感性和特异性之间具有最佳权衡（男性：74.6%（95%CI：70.7 - 78.2%）和65.1%（95%CI：59.7 - 70.3%），AUC 0.78（95%CI：0.75 - 0.81），P < 0.05；女性：65.8%（95%CI：60.3 - 71.0%）和80.3%（95%CI：75.7 - 84.3%），AUC 0.80（95%CI：0.77 - 0.
Zotero 插件