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高质量的基因组组装为水母的适应性进化提供了见解。

High-Quality Genome Assembly of Provides Insights Into the Adaptive Evolution of Jellyfish.

作者信息

Xia Wangxiao, Li Haorong, Cheng Wenmin, Li Honghui, Mi Yajing, Gou Xingchun, Liu Yaowen

机构信息

Shaanxi Key Laboratory of Brain Disorders, Institute of Basic Translational Medicine, Xi'an Medical University, Xi'an, China.

Center for Ecological and Environmental Sciences, Northwestern Polytechnical University, Xi'an, China.

出版信息

Front Genet. 2020 Jun 4;11:535. doi: 10.3389/fgene.2020.00535. eCollection 2020.

DOI:10.3389/fgene.2020.00535
PMID:32582283
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7287180/
Abstract

Jellyfish, such as , hold an important evolutionary position and have great ecological value. However, limited genomic resources are currently available for studying their basic genetic and development processes. Here, we assembled the first high-quality reference genome of , and successfully annotated 21,606 protein-coding genes. Codon usage analysis identified the frequent use of low-GC-content codons during protein-coding gene translation. Analysis of the relative evolution rate indicated that jellyfish had a faster evolution rate than sea anemones but slower rate than the species in Hydra. Phylogenetic analysis with two other species of jellyfish indicated that and have a closer relationship with each other than with , with divergence from their common ancestor occurring ≈475.7 million years ago. Our study not only showed the genomic characteristics and molecular adaptive evolution of , but also provides valuable genomic resources for further study on complex developmental processes and environmental adaptations.

摘要

诸如[具体水母名称未给出]的水母，具有重要的进化地位且具有巨大的生态价值。然而，目前用于研究其基本遗传和发育过程的基因组资源有限。在此，我们组装了首个高质量的[具体水母名称未给出]参考基因组，并成功注释了21,606个蛋白质编码基因。密码子使用分析确定了在蛋白质编码基因翻译过程中频繁使用低GC含量的密码子。相对进化速率分析表明，水母的进化速率比海葵快，但比水螅纲物种慢。与另外两种水母物种的系统发育分析表明，[具体水母名称未给出1]和[具体水母名称未给出2]彼此之间的关系比与[具体水母名称未给出3]的关系更密切，它们从共同祖先分歧发生在约4.757亿年前。我们的研究不仅展示了[具体水母名称未给出]的基因组特征和分子适应性进化，还为进一步研究复杂的发育过程和环境适应性提供了有价值的基因组资源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a1/7287180/e3b6a3fad2d1/fgene-11-00535-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a1/7287180/efbe12cedf47/fgene-11-00535-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a1/7287180/0e9801d33843/fgene-11-00535-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a1/7287180/28f7854cb0b3/fgene-11-00535-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a1/7287180/35f0201951f2/fgene-11-00535-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a1/7287180/21d3742657c8/fgene-11-00535-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a1/7287180/e3b6a3fad2d1/fgene-11-00535-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a1/7287180/efbe12cedf47/fgene-11-00535-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a1/7287180/0e9801d33843/fgene-11-00535-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a1/7287180/28f7854cb0b3/fgene-11-00535-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a1/7287180/35f0201951f2/fgene-11-00535-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a1/7287180/21d3742657c8/fgene-11-00535-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18a1/7287180/e3b6a3fad2d1/fgene-11-00535-g006.jpg

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2
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Gigascience. 2019 Jul 1;8(7). doi: 10.1093/gigascience/giz069.
3
bioRxiv. 2024 Aug 22:2024.08.21.608299. doi: 10.1101/2024.08.21.608299.
4
Jellyfish Venom Peptides Targeting Human Potassium Channels Identified through Ligand Screening: Morphometric and Molecular Identification of the Species and Antibiotic Potential.通过配体筛选鉴定的靶向人钾通道的水母毒液肽：物种的形态计量学和分子鉴定及抗生素潜力。
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Nat Commun. 2024 Jul 15;15(1):5936. doi: 10.1038/s41467-024-49848-z.
6
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PeerJ. 2023 Oct 16;11:e16188. doi: 10.7717/peerj.16188. eCollection 2023.
7
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Sci Rep. 2017 Dec 14;7(1):17583. doi: 10.1038/s41598-017-17484-x.
9
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10
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