Koul R, Razdan S, Motta A
Department of Neurology, Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar, India.
Epilepsia. 1988 Mar-Apr;29(2):116-22. doi: 10.1111/j.1528-1157.1988.tb04406.x.
The rural population of 63,645 living in the mountainous Kuthar Valley of South Kashmir, Northwest India was surveyed to determine the prevalence of major neurologic disorders, including epilepsy (called Lath/Mirgi/Laran in the local language). The survey was done according to a World Health Organization protocol (1981). House-to-house screening was done by Anganwadi workers to identify people with possible epilepsy. The screening questionnaire was translated into local vernacular. Persons who had some indication of a history of seizures or other neurologic disease were subsequently examined by a neurologic team. The diagnostic criteria of Hauser and Kurland (1975) were used to define cases of active epilepsy and seizure classification (ILAE, 1981) was done only with clinical data. One hundred fifty-seven cases of active epilepsy were detected, giving a crude prevalence rate of 2.47/1,000 general population. In those aged less than 14 years, prevalence was 3.18/1,000. Ninety-five (60.5%) of all cases were male; 91% of active epilepsy cases had onset of seizures before age 30 years. Mean age of onset in males was 5.3 years, and in females it was 7.1 years. Mean duration of seizures was 6 years; 78.9% cases had generalized seizures, 74.5% cases were receiving no specific treatment, 99.4% cases were born of home delivery, and 8.9% cases had a positive family history of seizures. Mental retardation was the most common associated abnormality in 22.9% of cases.
对居住在印度西北部克什米尔南部山区库萨尔山谷的63645名农村人口进行了调查,以确定包括癫痫(当地语言称为Lath/Mirgi/Laran)在内的主要神经系统疾病的患病率。该调查按照世界卫生组织的方案(1981年)进行。由anganwadi工作人员逐户筛查,以确定可能患有癫痫的人。筛查问卷被翻译成当地方言。有癫痫发作史或其他神经系统疾病迹象的人随后由神经科团队进行检查。采用豪泽和库兰德(1975年)的诊断标准来定义活动性癫痫病例,仅根据临床数据进行癫痫发作分类(国际抗癫痫联盟,1981年)。共检测到157例活动性癫痫病例,粗患病率为每1000名普通人群中2.47例。在14岁以下人群中,患病率为每1000名中3.18例。所有病例中95例(60.5%)为男性;91%的活动性癫痫病例在30岁之前开始发作。男性的平均发病年龄为5.3岁,女性为7.1岁。癫痫发作的平均持续时间为6年;78.9%的病例为全身性发作,74.5%的病例未接受特殊治疗,99.4%的病例为在家分娩,8.9%的病例有癫痫阳性家族史。智力迟钝是22.9%病例中最常见的相关异常情况。