伊朗鸦片、鸦片酊和美沙酮口服溶液中的铅污染情况。
Lead Contamination in Opium, Opium Tincture, and Methadone Oral Solution, in Iran.
作者信息
Rahimi Mitra, Eshraghi Mohammad Amin, Shadnia Shahin
机构信息
Toxicology Research Center, Excellence Center of Clinical Toxicology AND Department of Clinical Toxicology, Loghman Hakim Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Addict Health. 2020 Jan;12(1):34-39. doi: 10.22122/ahj.v12i1.258.
BACKGROUND
The present study is conducted with the aim to assess the lead contamination in opium tincture, methadone oral solution, and opium.
METHODS
10 samples from each of the matters of opium tinctures, methadone oral solutions, and opium (provided by the Law Enforcement Force of the Islamic Republic of Iran) were collected. Then, an atomic absorption spectrophotometer (AAS) was used to measure lead concentration in each of the samples. Data were analyzed using the SPSS software. A P value of 0.05 or less was considered to be statistically significant (Two-tailed).
FINDINGS
In this study, the amount of lead measured in all samples was equal or less than 5 parts per million (ppm) and the only exception was the lead level of 5.6 ppm in one of the opium tincture samples, which was slightly higher than the standard lead level.
CONCLUSION
The results of the current study showed that lead was present in opium tincture, methadone oral solution, and opium, but it was not in toxic levels. It is reasonable for opium derived medicinal products, but the low levels of lead in opium may need to be addressed at different times in different regions of the country.
背景
本研究旨在评估阿片酊、美沙酮口服溶液和鸦片中的铅污染情况。
方法
从阿片酊、美沙酮口服溶液和鸦片（由伊朗伊斯兰共和国执法部队提供）的每种物质中收集10个样本。然后，使用原子吸收分光光度计（AAS）测量每个样本中的铅浓度。数据使用SPSS软件进行分析。P值小于或等于0.05被认为具有统计学意义（双侧）。
结果
在本研究中，所有样本中测得的铅含量均等于或低于百万分之五（ppm），唯一的例外是一个阿片酊样本中的铅含量为5.6 ppm，略高于标准铅含量。
结论
本研究结果表明，阿片酊、美沙酮口服溶液和鸦片中存在铅，但未达到有毒水平。对于源自鸦片的药品来说这是合理的，但鸦片中铅含量较低的问题可能需要在该国不同地区的不同时间加以解决。
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