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伊朗东南部口服/吸入鸦片成瘾者与非成瘾对照组的血铅水平比较。

Comparing Blood Lead Level among Oral/inhaled Opium Addicts with a Non-addict Control Group in the Southeast of Iran.

作者信息

Nemati Alireza, Jafari Shima, Afshari Mahdi, Dahmardeh Somayeh, Tabrizian Kaveh

机构信息

Assistant Professor, Department of Internal Medicine, School of Medicine, Zabol University of Medical Sciences, Zabol, Iran.

PhD Student, Student Research Committee, School of Pharmacy, Zabol University of Medical Sciences, Zabol, Iran.

出版信息

Addict Health. 2016 Fall;8(4):235-241.

Abstract

BACKGROUND

Opium is widely used among addicts in the Middle East countries such as Iran. Recent reports suggest that opium sellers cheat their customers by adding lead to the opium. Contaminated opium can threaten the health of consumers. This study was designed to evaluate the lead concentration in blood sample of oral and inhaled opium user's referring to Amir Al-Momenin Hospital in Zabol, Iran, during spring 2015 in comparison with those of control group.

METHODS

Blood lead level (BLL) of 188 subjects with a mean age of 52.06 years in three categories - including oral opium addicted (55 patients), inhaled opium addicted (55 patients), and healthy control group (n = 78) - was assessed. The BLL of all the subjects was assessed using an atomic absorption spectrophotometer.

FINDINGS

Almost all participants consumed "Tariak" (99.09%). Mean ± standard deviation (SD) duration of opium addiction was 13.21 ± 10.26 years. The average blood lead concentration among oral users, inhaled users, and control group were 34.31 ± 21.54, 41.13 ± 26.40, and 9.86 ± 4.40 µg/dl, respectively (P = 0.001).

CONCLUSION

Our study showed significant differences of BLLs between opium users and control group. We also did not find any association between blood lead concentration and method of opium consumption.

摘要

背景

鸦片在伊朗等中东国家的成瘾者中广泛使用。最近的报告表明,鸦片卖家通过在鸦片中添加铅来欺骗顾客。受污染的鸦片会威胁消费者的健康。本研究旨在评估2015年春季转诊至伊朗扎博勒阿米尔·穆民医院的口服和吸入鸦片使用者血液样本中的铅浓度,并与对照组进行比较。

方法

评估了188名平均年龄为52.06岁的受试者的血铅水平(BLL),分为三类——包括口服鸦片成瘾者(55例患者)、吸入鸦片成瘾者(55例患者)和健康对照组(n = 78)。所有受试者的BLL均使用原子吸收分光光度计进行评估。

结果

几乎所有参与者都吸食“塔里亚克”(99.09%)。鸦片成瘾的平均持续时间±标准差(SD)为13.21±10.26年。口服使用者、吸入使用者和对照组的平均血铅浓度分别为34.31±21.54、41.13±26.40和9.86±4.40µg/dl(P = 0.001)。

结论

我们的研究表明,鸦片使用者和对照组之间的BLL存在显著差异。我们还未发现血铅浓度与鸦片消费方式之间存在任何关联。

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Presence of lead in opium.鸦片中铅的存在。
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