• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Fluoxetine and pargyline on the nucleus raphe magnus inhibition of cat multireceptive dorsal horn neurones.

作者信息

Khanna S, Sinclair J G

机构信息

Division of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada.

出版信息

Gen Pharmacol. 1988;19(2):249-52. doi: 10.1016/0306-3623(88)90070-5.

DOI:10.1016/0306-3623(88)90070-5
PMID:3258264
Abstract
  1. To determine whether serotonin (5-HT) is involved in the nucleus raphe magnus (NRM) inhibition of cat multireceptive dorsal horn neurones, the NRM inhibition was tested with drugs (fluoxetine and pargyline) that should enhance 5-HT synaptic activity. 2. Fluoxetine and pargyline systemically administered, individually or concurrently, decreased rather than increased the inhibition. 3. The results do not support the hypothesis that NRM stimulation-produced inhibition is mediated by 5-HT release.
摘要

相似文献

1
Fluoxetine and pargyline on the nucleus raphe magnus inhibition of cat multireceptive dorsal horn neurones.
Gen Pharmacol. 1988;19(2):249-52. doi: 10.1016/0306-3623(88)90070-5.
2
The failure of morphine to interact with serotonin on nucleus raphe magnus descending inhibition or morphine-induced suppression of cat spinal cord multireceptive neurones.吗啡在中缝大核下行抑制方面与5-羟色胺无相互作用，或吗啡对猫脊髓多感受神经元的抑制作用。
Gen Pharmacol. 1987;18(3):287-92. doi: 10.1016/0306-3623(87)90013-9.
3
Pathways mediating descending control of spinal nociceptive transmission from the nuclei locus coeruleus (LC) and raphe magnus (NRM) in the cat.介导猫中脑蓝斑核（LC）和中缝大核（NRM）对脊髓伤害性信息传递下行控制的通路。
Exp Brain Res. 1986;61(3):597-606. doi: 10.1007/BF00237586.
4
Mechanisms mediating the brain stem control of somatosensory transmission in the dorsal horn of the cat's spinal cord: an intracellular analysis.介导猫脊髓背角体感传递的脑干控制机制：细胞内分析
Exp Brain Res. 1987;69(1):93-106. doi: 10.1007/BF00247032.
5
Quantitative comparison of inhibition in spinal cord of nociceptive information by stimulation in periaqueductal gray or nucleus raphe magnus of the cat.猫中脑导水管周围灰质或中缝大核刺激对脊髓伤害性信息抑制作用的定量比较
J Neurophysiol. 1983 Dec;50(6):1433-45. doi: 10.1152/jn.1983.50.6.1433.
6
Inhibition of spinal nociceptive neurons by microinjections of somatostatin into the nucleus raphe magnus and the midbrain periaqueductal gray of the anesthetized cat.通过向麻醉猫的中缝大核和中脑导水管周围灰质微量注射生长抑素对脊髓伤害性神经元的抑制作用
Neurosci Lett. 1995 Mar 3;187(2):137-41. doi: 10.1016/0304-3940(95)11345-2.
7
Descending control of spinal nociceptive transmission. Actions produced on spinal multireceptive neurones from the nuclei locus coeruleus (LC) and raphe magnus (NRM).脊髓伤害性感受传递的下行控制。蓝斑核（LC）和中缝大核（NRM）对脊髓多感受神经元产生的作用。
Exp Brain Res. 1985;58(2):213-26. doi: 10.1007/BF00235305.
8
Differential effects of fluoxetine and zimelidine on the uptake of 5-hydroxytryptamine and tryptamine by cortical slices and on responses of cortical neurones to stimulation of the nucleus raphe medianus.氟西汀和齐美利定对皮质切片摄取5-羟色胺和色胺的差异作用以及对皮质神经元对中缝正中核刺激反应的差异作用。
Eur J Pharmacol. 1982 Jul 30;81(4):681-5. doi: 10.1016/0014-2999(82)90361-2.
9
Serotoninergic and non-serotoninergic responses of phrenic motoneurones to raphe stimulation in the cat.猫膈运动神经元对中缝刺激的5-羟色胺能和非5-羟色胺能反应
J Physiol. 1986 Nov;380:373-85. doi: 10.1113/jphysiol.1986.sp016291.
10
Raphe magnus stimulation-induced antinociception in the cat is associated with release of amino acids as well as serotonin in the lumbar dorsal horn.中缝大核刺激诱导的猫抗伤害感受与腰段背角中氨基酸以及5-羟色胺的释放有关。
Brain Res. 1993 Jul 30;618(1):95-108. doi: 10.1016/0006-8993(93)90433-n.