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贲门失弛缓症与肥胖:腹腔镜 Heller 肌切开术和 Dor 胃底折叠术后患者的结局和感受。

Achalasia and obesity: patient outcomes and impressions following laparoscopic Heller myotomy and Dor fundoplication.

机构信息

Department of General Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.

, Boston, USA.

出版信息

Langenbecks Arch Surg. 2020 Sep;405(6):809-816. doi: 10.1007/s00423-020-01912-0. Epub 2020 Jun 25.

DOI:10.1007/s00423-020-01912-0
PMID:32583213
Abstract

PURPOSE

The optimal management of achalasia in obese patients is unclear. For those who have undergone Heller myotomy and fundoplication, the long-term outcomes and their impressions following surgery are largely unknown.

METHODS

A retrospective review of patients who underwent laparoscopic Heller myotomy and Dor fundoplication (LHMDF) for achalasia was performed. From this cohort, Class 2 and 3 obese (BMI > 35 kg/m) patients were identified for short- and long-term outcome analysis.

RESULTS

Between 2003 and 2015, 252 patients underwent LHMDF for achalasia, and 17 (7%) patients had BMI > 35 kg/m. Pre-operative Eckardt scores varied from 2 to 9, and at short-term (2-4 week) follow-up, scores were 0 or 1. Ten (58%) patients had available long-term (2-144 months) follow-up data. Eckardt scores at this time ranged from 0 to 6. Symptom recurrence was worse for patients with BMI > 40 kg/m compared to patients with BMI < 40 kg/m. BMI was largely unchanged at long-term follow-up regardless of pre-intervention BMI. Most patients were satisfied with surgery but would have considered a combined LHMDF and weight-loss procedure had it been offered.

CONCLUSION

LHMDF for achalasia in obese patients is safe and effective in the short term. At long-term follow-up, many patients had symptom recurrence and experienced minimal weight loss. Discussing weight-loss surgery at the time LHMDF may be appropriate to ensure long-term achalasia symptom relief.

摘要

目的

肥胖患者贲门失弛缓症的最佳治疗方法仍不明确。对于接受过 Heller 肌切开术和胃底折叠术的患者,其长期疗效和术后感受在很大程度上尚未可知。

方法

回顾性分析了接受腹腔镜 Heller 肌切开术和 Dor 胃底折叠术(LHMDF)治疗贲门失弛缓症的患者。在此队列中,确定了 2 型和 3 型肥胖(BMI>35kg/m²)患者进行短期和长期结果分析。

结果

2003 年至 2015 年间,252 例患者接受了 LHMDF 治疗贲门失弛缓症,其中 17 例(7%)患者 BMI>35kg/m²。术前 Eckardt 评分从 2 到 9 不等,短期(2-4 周)随访时评分为 0 或 1。10 例(58%)患者有长期(2-144 个月)随访数据。此时的 Eckardt 评分范围为 0 到 6。BMI>40kg/m²的患者症状复发较 BMI<40kg/m²的患者更差。无论术前 BMI 如何,长期随访时 BMI 基本保持不变。大多数患者对手术满意,但如果有联合 LHMDF 和减肥手术的选择,他们可能会考虑。

结论

对于肥胖患者的贲门失弛缓症,LHMDF 短期治疗安全有效。在长期随访中,许多患者出现症状复发,体重减轻很少。在进行 LHMDF 时讨论减肥手术可能是合适的,以确保长期的贲门失弛缓症症状缓解。

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本文引用的文献

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Am Surg. 2018 Apr 1;84(4):501-505.