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Age-related decline of de novo T cell responsiveness as a cause of COVID-19 severity.

作者信息

Nicoli Francesco, Solis-Soto Maria Teresa, Paudel Deepak, Marconi Peggy, Gavioli Riccardo, Appay Victor, Caputo Antonella

机构信息

Department of Chemical and Pharmaceutical Sciences, University of Ferrara, Via Fossato di Mortara 64/B, 44121, Ferrara, Italy.

Universidad de O'Higgins, Rancagua, Chile.

出版信息

Geroscience. 2020 Aug;42(4):1015-1019. doi: 10.1007/s11357-020-00217-w. Epub 2020 Jun 24.

DOI:10.1007/s11357-020-00217-w
PMID:32583231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7312114/
Abstract
摘要

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Cell. 2020 Jun 25;181(7):1489-1501.e15. doi: 10.1016/j.cell.2020.05.015. Epub 2020 May 20.
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Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19).新型冠状病毒病（COVID-19）患者 T 细胞减少和功能耗竭。
Front Immunol. 2020 May 1;11:827. doi: 10.3389/fimmu.2020.00827. eCollection 2020.
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Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals.
年龄差异会影响腺病毒和 mRNA 疫苗对 COVID-19 诱导的适应性免疫反应。
Nat Aging. 2024 Aug;4(8):1121-1136. doi: 10.1038/s43587-024-00644-w. Epub 2024 Jun 25.
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Distinct T cell responsiveness to different COVID-19 vaccines and cross-reactivity to SARS-CoV-2 variants with age and CMV status.不同 COVID-19 疫苗引起的 T 细胞反应不同，以及与年龄和 CMV 状态相关的对 SARS-CoV-2 变体的交叉反应性。
Front Immunol. 2024 May 7;15:1392477. doi: 10.3389/fimmu.2024.1392477. eCollection 2024.
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J Family Med Prim Care. 2023 Sep;12(9):1965-1971. doi: 10.4103/jfmpc.jfmpc_2491_22. Epub 2023 Sep 30.
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