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家庭氧气治疗导致的烧伤死亡率超过预期。

Mortality From Burns Sustained on Home Oxygen Therapy Exceeds Predicted Mortality.

机构信息

Department of Surgery, University of Cincinnati, Ohio.

出版信息

J Burn Care Res. 2020 Sep 23;41(5):976-980. doi: 10.1093/jbcr/iraa097.

DOI:10.1093/jbcr/iraa097
PMID:32583846
Abstract

The Boston Criteria and the Abbreviated Burn Severity Index are two widely accepted models for predicting mortality in burn patients. We aimed to elucidate whether these models are able to predict the risk of mortality in patients who sustain burns while smoking on home oxygen given their clinical fragility. We conducted a retrospective chart review of 48 patients admitted to our burn center from November 2013 to September 2017 who sustained a burn while smoking on home oxygen. Yearlong mortality was the primary outcome of the investigation; secondary outcomes included discharge to facility, length of stay, and need for tracheostomy. We calculated the expected mortality rate for each patient based on Boston Criteria and Abbreviated Burn Severity Index and compared the mortality rate observed in our cohort. Patients in our cohort suffered a 54% mortality rate within a year of injury, compared to a 23.5% mortality predicted by Boston Criteria, which was found to be statistically significant by chi-square analysis (P < .05). Abbreviated Burn Severity Index predicted mortality was 19.7%. While the absolute value of the difference in mortality was greater, this was not significant on chi-square analysis due to sample size. Our secondary outcomes revealed 42% discharge to facility, the average length of stay of 6.2 days, and 6.25% required tracheostomy. Patients whose burns are attributable to smoking on home oxygen may have an increased risk of mortality than prognostication models would suggest. This bears significant clinical impact, particularly regarding family and provider decision making in pursuing aggressive management.

摘要

波士顿标准和简化烧伤严重度指数是两种广泛接受的预测烧伤患者死亡率的模型。我们旨在阐明这些模型是否能够预测在家庭吸氧时吸烟导致烧伤的患者的死亡风险,考虑到他们的临床脆弱性。我们对 2013 年 11 月至 2017 年 9 月期间因家庭吸氧时吸烟导致烧伤而入住我们烧伤中心的 48 名患者进行了回顾性图表审查。研究的主要结局是 1 年死亡率;次要结局包括出院到医疗机构、住院时间和需要气管切开术。我们根据波士顿标准和简化烧伤严重度指数计算了每位患者的预期死亡率,并比较了我们队列中的死亡率。我们队列中的患者在受伤后 1 年内的死亡率为 54%,而波士顿标准预测的死亡率为 23.5%,这通过卡方分析发现具有统计学意义(P <.05)。简化烧伤严重度指数预测的死亡率为 19.7%。虽然死亡率的差异绝对值更大,但由于样本量,卡方分析未发现差异具有统计学意义。我们的次要结局显示 42%的患者出院到医疗机构,平均住院时间为 6.2 天,6.25%的患者需要气管切开术。因家庭吸氧时吸烟导致烧伤的患者的死亡率可能高于预测模型所提示的死亡率。这具有重要的临床影响,特别是在家庭和提供者决定采取积极治疗时。

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J Burn Care Res. 2020 Sep 23;41(5):976-980. doi: 10.1093/jbcr/iraa097.
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