Xie Pei, Yang Shoushan, Guo Yuyu, Cai Zhihua, Dai Bin, He Lin
Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering, Shihezi University, Xinjiang Uygur Autonomous Region, Shihezi 832000, China.
J Org Chem. 2020 Jul 17;85(14):8872-8880. doi: 10.1021/acs.joc.0c00745. Epub 2020 Jul 5.
The first synthesis of benzyne-derived stable zwitterions is reported. Benzynes generated from 2-(trimethylsilyl)aryl triflates undergo a multicomponent reaction with phosphines and CO to produce the stable 1,5-zwitterionic species in moderate to excellent isolated yields, which provides a novel method for the preparation of phosphonium inner salts under mild and transition-metal-free conditions.
据报道，首次合成了苯炔衍生的稳定两性离子。由2-（三甲基甲硅烷基）芳基三氟甲磺酸酯生成的苯炔与膦和一氧化碳发生多组分反应，以中等至优异的分离产率生成稳定的1,5-两性离子物种，这为在温和且无过渡金属的条件下制备鏻内盐提供了一种新方法。
