Chikwendu Justina Ndirika, Udenta Elizabeth Anamenechukwu, Nwakaeme Timothy Chukwuka
Department of Nutrition and Dietetics, University of Nigeria, Nsukka, Nigeria.
J Med Food. 2021 Mar;24(3):267-272. doi: 10.1089/jmf.2020.0017. Epub 2020 Jun 23.
Avocado pear pulp () is indigenous to Mexico. It is widely cultivated and consumed all over the world. Its oil is rich in monounsaturated fatty acids (SFAs) and can be used to replace SFAs in a diet to lower low-density lipoprotein (LDL) and raise high-density lipoprotein (HDL). Consumers seek healthy foods that aid in reducing metabolic syndrome. The aim of this study is to evaluate the effects of the best acceptable cakes supplemented with 0%, 10%, 30%, and 50% avocado on the serum lipid profile and plasma protein in rats. Twenty-five rats separated into five groups of four test groups and one control group were fed individually for 14 days, after which blood samples were withdrawn and subjected to biochemical analysis. Intake of cake supplemented with avocado pear pulp resulted in significant ( < .05) increment in the body weight, total cholesterol, triglycerides and HDL, and serum protein and decrement in LDL of the rats. The group fed 50% supplemented cake showed highest increase in HDL and least decrease in LDL. Cake supplemented with 50% avocado pear pulp proved to be a better supplementation in reducing serum LDL and increasing serum HDL and serum protein in rats, indicating to be a promising nutraceutical for the management of cardiovascular diseases and its associated complications.
鳄梨果肉原产于墨西哥。它在世界各地广泛种植和食用。其油富含单不饱和脂肪酸(SFAs),可用于替代饮食中的SFAs,以降低低密度脂蛋白(LDL)并提高高密度脂蛋白(HDL)。消费者追求有助于减少代谢综合征的健康食品。本研究的目的是评估添加0%、10%、30%和50%鳄梨的最佳可接受蛋糕对大鼠血脂谱和血浆蛋白的影响。将25只大鼠分为四个试验组和一个对照组,每组五只,单独喂养14天,之后采集血样并进行生化分析。摄入添加鳄梨果肉的蛋糕导致大鼠体重、总胆固醇、甘油三酯和HDL以及血清蛋白显著增加(<0.05),LDL减少。喂食50%添加蛋糕的组HDL增加最多,LDL减少最少。添加50%鳄梨果肉的蛋糕被证明是降低大鼠血清LDL、增加血清HDL和血清蛋白的更好补充剂,表明它是一种有前途的营养保健品,可用于管理心血管疾病及其相关并发症。