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猪肠道微生物组的终身动态及其对益生菌开发和食品安全的影响。

Life-long dynamics of the swine gut microbiome and their implications in probiotics development and food safety.

机构信息

Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, College of Life Science and Engineering, Foshan University , Foshan, China.

Department of Animal Science, Division of Agriculture, University of Arkansas , Fayetteville, AR, USA.

出版信息

Gut Microbes. 2020 Nov 1;11(6):1824-1832. doi: 10.1080/19490976.2020.1773748. Epub 2020 Jun 25.

DOI:10.1080/19490976.2020.1773748
PMID:32584645
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7524149/
Abstract

The swine gut microbiome has received remarkable attention in recent years given that pigs serve not only as important sources for animal-derived food but also as excellent biomedical models for human health. However, despite recent advances in the understanding of the swine gut microbiome, many important biological and ecological questions are still largely unanswered. In a recent study, we characterized the life-long dynamics of the swine gut microbiome from birth to market. We showed distinct shifts in gut microbiome structure along different growth stages mainly driven by diet. Here, we summarize these discoveries and provide additional data related to the core swine gut microbiome, probiotics development in the swine industry, and foodborne pathogens in the pork supply chain.

摘要

近年来,猪的肠道微生物组受到了极大的关注,因为猪不仅是动物源性食品的重要来源,而且还是人类健康的优秀生物医学模型。然而,尽管近年来对猪的肠道微生物组有了更多的了解,但许多重要的生物学和生态学问题仍然很大程度上没有得到解答。在最近的一项研究中,我们描述了猪的肠道微生物组从出生到上市的终身动态。我们发现,肠道微生物组结构在不同的生长阶段发生了明显的变化,主要是由饮食驱动的。在这里,我们总结了这些发现,并提供了与核心猪肠道微生物组、猪产业中的益生菌开发以及猪肉供应链中的食源性病原体相关的其他数据。

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