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并非医嘱:非法吸毒人群中出于非医疗目的使用处方药的动机。

Not what the doctor ordered: Motivations for nonmedical prescription drug use among people who use illegal drugs.

机构信息

Substance Use Research Group (SURG), Centre for Criminology, University of South Wales, Pontypridd, CF37 1DL, Wales.

Substance Use Research Group (SURG), Centre for Criminology, University of South Wales, Pontypridd, CF37 1DL, Wales.

出版信息

Int J Drug Policy. 2020 Aug;82:102823. doi: 10.1016/j.drugpo.2020.102823. Epub 2020 Jun 23.

Abstract

BACKGROUND

Nonmedical Prescription Drug Use (NMPDU) is common among people who use illegal drugs. NMPDU is particularly problematic among this population however, as medications such as benzodiazepines and gabapentinoids can potentiate the harmful effects of opioids. Despite these harms, there is some evidence that NMPDU can have harm reducing and therapeutic potential for some people who use illegal drugs. This study provides further evidence of the harm reducing motives for NMPDU among people who use illegal drugs in community and prison settings in Wales, UK.

METHODS

In depth, semi-structured interviews were conducted with 60 interviewees recruited from statutory and third sector drug treatment providers operating in five towns and cities in Wales, and from two Welsh prisons. Eligibility was based primarily on whether the person was currently (or previously) a user of illegal drugs and had recent experience of NMPDU.

RESULTS

NMPDU was found to be largely driven by insufficient access to certain prescription medications and treatment. In this context, NMPDU played an important role in alleviating legitimate medical concerns and overcoming logistical and regulatory barriers associated with Opioid Substitution Therapy. NMPDU also had everyday practicality and mitigated many of the everyday harms experienced by people who use drugs, including opioid withdrawal and stimulant comedowns.

CONCLUSION

Results suggest that NMPDU has the potential to mitigate a number of legitimate medical concerns in the absence of treatment. Finding nuanced ways of responding to patient need whilst reducing the potential for NMPDU are therefore needed, and harm reduction strategies that harness the knowledge and expertise of people who use drugs should be encouraged. Additional policy measures that attend to the inequities and social-structural factors that produce and maintain the need to consume prescription medications in ways that are not intended are also required.

摘要

背景

非医疗处方药物使用(NMPDU)在使用非法药物的人群中很常见。然而,对于这类人群来说,NMPDU 尤其成问题,因为苯二氮䓬类药物和加巴喷丁类药物等药物会增强阿片类药物的有害作用。尽管存在这些危害,但有一些证据表明,对于一些使用非法药物的人来说,NMPDU 可能具有减少伤害和治疗的潜力。本研究进一步证明了在英国威尔士的社区和监狱环境中,使用非法药物的人使用 NMPDU 的减少伤害动机。

方法

通过深入的半结构化访谈,对来自威尔士五个城镇和两个威尔士监狱的 60 名受访者进行了采访。这些受访者是从提供法定和第三部门药物治疗的提供者中招募的,他们的入选标准主要是是否当前(或以前)是非法药物使用者,并且有最近使用 NMPDU 的经验。

结果

研究发现,NMPDU 主要是由于无法获得某些处方药物和治疗而导致的。在这种情况下,NMPDU 在缓解合法的医疗关注和克服与阿片类药物替代治疗相关的后勤和监管障碍方面发挥了重要作用。NMPDU 还具有日常实用性,可以减轻吸毒者所经历的许多日常危害,包括阿片类药物戒断和兴奋剂戒断。

结论

结果表明,在缺乏治疗的情况下,NMPDU 有可能减轻许多合法的医疗关注。因此,需要找到细致入微的方法来满足患者的需求,同时减少 NMPDU 的潜在风险,并鼓励利用吸毒者的知识和专业知识的减少伤害策略。还需要采取额外的政策措施,解决产生和维持以非预期方式使用处方药物的不平等和社会结构因素。

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