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糖尿病与心力衰竭:一对不搭的伴侣。

Diabetes and Heart Failure: A Marriage of Inconvenience.

机构信息

Endocrinology and Metabolism Institute, Cleveland Clinic, 9500 Euclid Avenue, F-20, Cleveland, OH 44195, USA.

Section of Heart Failure and Cardiac Transplant Medicine, Cleveland Clinic, 9500 Euclid Avenue, J3-4, Cleveland, OH 44195, USA. Electronic address: https://twitter.com/SBhattacharyaMD.

出版信息

Clin Geriatr Med. 2020 Aug;36(3):447-455. doi: 10.1016/j.cger.2020.04.005. Epub 2020 Apr 17.

Abstract

Type 2 diabetes and congestive heart failure are growing public health problems and are expected to worsen in the next decade. There is an inarguable link between diabetes and heart failure but only recently has there been an effort to elucidate the underlying pathophysiologic connection resulting in diabetic cardiomyopathy. Traditionally, diabetes and heart failure have been treated as 2 distinct disease entities, but recent advances in individual therapies have shown remarkable concomitant improvements in both diabetes and cardiovascular outcomes. This article aims to review the key connections in the epidemiology and etiopathophysiology of type 2 diabetes and heart failure.

摘要

2 型糖尿病和充血性心力衰竭是日益严重的公共卫生问题,预计在未来十年内会恶化。糖尿病和心力衰竭之间存在不可否认的联系,但直到最近才努力阐明导致糖尿病心肌病的潜在病理生理联系。传统上,糖尿病和心力衰竭被视为两种不同的疾病实体,但最近在个体治疗方面的进展表明,糖尿病和心血管结局都有显著的同时改善。本文旨在综述 2 型糖尿病和心力衰竭的流行病学和病理生理学中的关键联系。

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