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喉全切除术后的康复:肿瘤学、功能、社会职业和心理方面。

Rehabilitation following total laryngectomy: Oncologic, functional, socio-occupational and psychological aspects.

机构信息

Service ORL et CCF, CHU Angers, 4, rue Larrey, 49100 Angers, France.

Service ORL et CCF, CHU Angers, 4, rue Larrey, 49100 Angers, France.

出版信息

Eur Ann Otorhinolaryngol Head Neck Dis. 2021 Jan;138(1):19-22. doi: 10.1016/j.anorl.2020.06.006. Epub 2020 Jun 22.

DOI:10.1016/j.anorl.2020.06.006
PMID:32586777
Abstract

GOAL

To review rehabilitation following total laryngectomy by an analysis of epidemiological, oncologic and functional data.

MATERIALS AND METHODS

This retrospective observational study focused on patients having undergone total laryngectomy or pharyngolaryngectomy between January 1, 2005 and December 31, 2016. Oncologic data notably comprised survival and relapse and predictive factors. The impact of the procedure on quality of life and the voice was analyzed by self-administered questionnaires (EORTC QLQ-C30 and H&N35, VHI 30). A satisfaction questionnaire was also sent to patients.

RESULTS

One hundred and thirty three patients were included. Overall specific 5-year survival was 65%. The relapse rate was 32%. Factors influencing survival were WHO performance status ≥2 (P<0.05), tumor location (P=0.07), metastatic lymphadenopathy (P=0.017) and positive resection margins (P=0.01). Quality of life was moderately degraded (global EORTC QLQ-C30 status: 61.4±23.9). Type of rehabilitation (P=0.03), tube feeding (P=0.03) and relapse (P<0.01) influenced quality of life. There were no differences in voice quality according to rehabilitation method, and no predictive factors for failure of voice rehabilitation. More than 90% of patients were satisfied with their hospital stay; 43%, however, were not satisfied with community caregiver training for laryngectomy patients.

CONCLUSION

Rehabilitation of laryngectomized patients is a current therapeutic challenge. A therapeutic education tool was designed to better meet patient expectations.

摘要

目的

通过分析流行病学、肿瘤学和功能数据来回顾喉全切除术后的康复情况。

材料与方法

本回顾性观察研究聚焦于 2005 年 1 月 1 日至 2016 年 12 月 31 日期间行全喉切除术或咽-喉切除术的患者。肿瘤学数据主要包括生存和复发情况以及预测因素。通过自我管理问卷(EORTC QLQ-C30 和 H&N35、VHI 30)分析手术对生活质量和嗓音的影响。还向患者发送了一份满意度问卷。

结果

共纳入 133 例患者。总体特异性 5 年生存率为 65%。复发率为 32%。影响生存的因素包括:WHO 体能状态≥2(P<0.05)、肿瘤位置(P=0.07)、转移性淋巴结病(P=0.017)和阳性切缘(P=0.01)。生活质量中度受损(全球 EORTC QLQ-C30 状态:61.4±23.9)。康复方式(P=0.03)、管饲(P=0.03)和复发(P<0.01)影响生活质量。康复方式对嗓音质量无差异,且嗓音康复失败无预测因素。超过 90%的患者对住院治疗满意;然而,43%的患者对喉切除术患者的社区护理培训不满意。

结论

喉切除患者的康复是当前治疗的挑战。设计了一种治疗教育工具,以更好地满足患者的期望。

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Eur Ann Otorhinolaryngol Head Neck Dis. 2021 Jan;138(1):19-22. doi: 10.1016/j.anorl.2020.06.006. Epub 2020 Jun 22.
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