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Potential contribution of increased soluble IL-2R to lymphopenia in COVID-19 patients.

作者信息

Zhang Yaguang, Wang Xiaojing, Li Xuezhen, Xi Dong, Mao Ruizhi, Wu Xiaohui, Cheng Shipeng, Sun Xiaoyu, Yi Chunyan, Ling Zhiyang, Ma Liyan, Ning Qin, Fang Yiru, Sun Bing, Wu Di

机构信息

State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, 320 Yueyang Road, 200031, Shanghai, China.

Department and Institute of Infectious Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, China.

出版信息

Cell Mol Immunol. 2020 Aug;17(8):878-880. doi: 10.1038/s41423-020-0484-x. Epub 2020 Jun 25.

DOI:10.1038/s41423-020-0484-x
PMID:32587367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7315399/
Abstract
摘要

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Hosp Pediatr. 2020 Jun;10(6):537-540. doi: 10.1542/hpeds.2020-0123. Epub 2020 Apr 7.
2
Increased soluble interleukin-2 receptor concentration in plasma predicts a decreased cellular response to IL-2.血浆中可溶性白细胞介素-2受体浓度升高预示着细胞对白细胞介素-2的反应降低。
Br J Cancer. 1995 Aug;72(2):452-5. doi: 10.1038/bjc.1995.354.
中国奥密克戎流行期间,重症和危重症奥密克戎感染患者的免疫和炎症特征。
BMC Infect Dis. 2024 Aug 9;24(1):809. doi: 10.1186/s12879-024-09652-y.
4
Elevated CD4 T Cell Senescence Associates with Impaired Immune Responsiveness in Severe COVID-19.CD4 T细胞衰老加剧与重症COVID-19患者免疫反应受损有关。
Aging Dis. 2024 Feb 17;16(1):498-511. doi: 10.14336/AD.2024.0214-2.
5
Integrated analysis of RNA-seq datasets reveals novel targets and regulators of COVID-19 severity.RNA-seq 数据集的综合分析揭示了 COVID-19 严重程度的新靶点和调控因子。
Life Sci Alliance. 2024 Jan 23;7(4). doi: 10.26508/lsa.202302358. Print 2024 Apr.
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COVID severity test (CoST sensor)-An electrochemical immunosensing approach to stratify disease severity.新冠严重程度测试(CoST传感器)——一种用于分层疾病严重程度的电化学免疫传感方法。
Bioeng Transl Med. 2023 Jul 11;8(5):e10566. doi: 10.1002/btm2.10566. eCollection 2023 Sep.
7
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J Allergy Clin Immunol. 2024 Jan;153(1):309-319. doi: 10.1016/j.jaci.2023.07.008. Epub 2023 Jul 29.
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