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一名患疟疾的日本男子在肯尼亚农村待了6个月后,发热检测呈阴性。

A Japanese man with malaria tests negative for fever after spending 6 months in rural Kenya.

作者信息

Sugimoto Takashi, Takahashi Kensuke, Matsui Kosuke, Asada Masahito, Kaneko Osamu, Ariyoshi Koya

机构信息

Department of Infectious Diseases, Nagasaki University Hospital, Nagasaki University, Nagasaki, Japan.

Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.

出版信息

Trop Med Health. 2020 Jun 24;48:52. doi: 10.1186/s41182-020-00220-z. eCollection 2020.

DOI:10.1186/s41182-020-00220-z
PMID:32587463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7313188/
Abstract

A previously healthy Japanese man in his fifties was admitted to our hospital because of a recurrent fever after returning from Kenya and Madagascar. He was ambulant with a body temperature of 36.6 °C. His physical examination revealed normal except for tender hepatomegaly. The blood test results showed no apparent abnormality except thrombocytopenia and mild liver dysfunction. The rapid diagnostic test and Giemsa-stained blood film were repeatedly negative for malaria. Computed tomography scans of the chest, abdomen, and pelvis revealed no significantly abnormal findings.

摘要

一名五十多岁此前身体健康的日本男子,因从肯尼亚和马达加斯加回国后反复发热而入住我院。他体温为36.6℃,可自行走动。体格检查发现除肝脏压痛性肿大外均正常。血液检查结果除血小板减少和轻度肝功能障碍外无明显异常。疟疾快速诊断试验和吉姆萨染色血涂片多次呈阴性。胸部、腹部和骨盆的计算机断层扫描未发现明显异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef28/7313188/defb93f3179e/41182_2020_220_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef28/7313188/defb93f3179e/41182_2020_220_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef28/7313188/defb93f3179e/41182_2020_220_Fig1_HTML.jpg

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本文引用的文献

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Two cases of long-lasting, sub-microscopic Plasmodium malariae infections in adults from coastal Tanzania.坦桑尼亚沿海地区两例成人持久亚微观疟原虫感染。
Malar J. 2019 Apr 29;18(1):149. doi: 10.1186/s12936-019-2787-x.
2
Parasitemia and Band Sensitivity of the SD Bioline Malaria Ag P.f/Pan Rapid Diagnostic Test in Madagascar.SD Bioline 疟疾抗原 P.f/ 盘快速诊断检测在马达加斯加的寄生虫血症和带敏感性。
Am J Trop Med Hyg. 2019 May;100(5):1196-1201. doi: 10.4269/ajtmh.18-1013.
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Plasmodium malariae Prevalence and csp Gene Diversity, Kenya, 2014 and 2015.
2014年和2015年肯尼亚疟原虫疟疾流行情况及环子孢子蛋白(csp)基因多样性
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UK malaria treatment guidelines 2016.《2016年英国疟疾治疗指南》
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