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快速免疫层析法检测疟原虫抗原对检测间日疟原虫和卵形疟原虫不可靠。

Rapid immunochromatographic malarial antigen detection unreliable for detecting Plasmodium malariae and Plasmodium ovale.

作者信息

Grobusch M P, Hänscheid T, Zoller T, Jelinek T, Burchard G D

机构信息

Department of Parasitology, Institute of Tropical Medicine, Eberhard Karls University, Wilhelmstrasse 27, 72074 Tübingen, Germany.

出版信息

Eur J Clin Microbiol Infect Dis. 2002 Nov;21(11):818-20. doi: 10.1007/s10096-002-0831-0. Epub 2002 Nov 7.

DOI:10.1007/s10096-002-0831-0
PMID:12461593
Abstract

In order to determine the reliability of two commercial tests for the rapid detection of plasmodial antigen in cases of infection with Plasmodium ovale and Plasmodium malariae, the products were evaluated in four centers and a search of the relevant literature was performed. The results of the present and previous studies were compared. With overall sensitivities ranging between 18.8% and 47.6% for Plasmodium malariae and between 20% and 31.3% for Plasmodium ovale, it is evident that neither test is reliable for the detection of Plasmodium ovale and Plasmodium malariae infections.

摘要

为了确定两种用于快速检测卵形疟原虫和三日疟原虫感染病例中疟原虫抗原的商业检测方法的可靠性,在四个中心对这些产品进行了评估,并检索了相关文献。将本研究结果与之前的研究结果进行了比较。对于三日疟原虫,总体敏感性在18.8%至47.6%之间,对于卵形疟原虫,总体敏感性在20%至31.3%之间,显然这两种检测方法都不可靠,无法检测卵形疟原虫和三日疟原虫感染。

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