Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Cardiac Surgery Unit, Lancisi Cardiovascular Center, Polytechnic University of Marche, Ospedali Riuniti, Ancona, Italy.
Eur J Cardiothorac Surg. 2020 Nov 1;58(5):1063-1071. doi: 10.1093/ejcts/ezaa154.
Minimally invasive surgical techniques with optimal outcomes are of paramount importance. Sutureless and rapid deployment aortic valves are increasingly implanted via minimally invasive approaches. We aimed to analyse the procedural outcomes of a full sternotomy (FS) compared with those of minimally invasive cardiac surgery (MICS) and further assess MICS, namely ministernotomy (MS) and anterior right thoracotomy (ART).
We selected all isolated aortic valve replacements in the Sutureless and Rapid Deployment Aortic Valve Replacement International Registry (SURD-IR, n = 2257) and performed propensity score matching to compare aortic valve replacement through FS or MICS (n = 508/group) as well as through MS and ART accesses (n = 569/group).
Postoperative mortality was 1.6% in FS and MICS patients who had a mean logistic EuroSCORE of 11%. Cross-clamp and cardiopulmonary bypass (CPB) times were shorter in the FS group than in the MICS group (mean difference 3.2 and 9.2 min; P < 0.001). Patients undergoing FS had a higher rate of acute kidney injury (5.6% vs 2.8%; P = 0.012). Direct comparison of MS and ART revealed longer mean cross-clamp and CPB times (12 and 16.7 min) in the ART group (P < 0.001). The postoperative outcome revealed a higher stroke rate (3.2% vs 1.2%; P = 0.043) as well as a longer postoperative intensive care unit [2 (1-3) vs 1 (1-3) days; P = 0.009] and hospital stay [11 (8-16) vs 8 (7-12) days; P < 0.001] in the MS group than in the ART group.
According to this non-randomized international registry, FS resulted in a higher rate of acute kidney injury. The ART access showed a lower stroke rate than MS and a shorter hospital stay than all other accesses. All these findings may be related to underlying patient risk factors.
微创技术与最佳疗效至关重要。无缝合、快速扩张的主动脉瓣越来越多地通过微创途径植入。我们旨在分析经胸骨正中切开术(FS)与微创心脏手术(MICS)的手术结果,并进一步评估 MICS,即胸骨下段小切口(MS)和右前外侧开胸术(ART)。
我们从无缝合和快速扩张主动脉瓣置换国际注册研究(SURD-IR)中选择了所有孤立的主动脉瓣置换术患者,并进行了倾向评分匹配,以比较 FS 与 MICS(每组 508 例)以及 MS 和 ART 入路(每组 569 例)的主动脉瓣置换术。
FS 和 MICS 患者的术后死亡率为 1.6%,平均逻辑 EuroSCORE 为 11%。FS 组的体外循环(CPB)和主动脉阻断时间均短于 MICS 组(平均差异 3.2 和 9.2 分钟;P<0.001)。FS 组急性肾损伤发生率较高(5.6% vs 2.8%;P=0.012)。MS 和 ART 的直接比较显示,ART 组的平均主动脉阻断和 CPB 时间较长(12 和 16.7 分钟;P<0.001)。术后结果显示,MS 组的卒中发生率较高(3.2% vs 1.2%;P=0.043),术后重症监护病房时间[2(1-3)天 vs 1(1-3)天;P=0.009]和住院时间[11(8-16)天 vs 8(7-12)天;P<0.001]也较长。
根据这项非随机国际注册研究,FS 导致急性肾损伤的发生率较高。ART 入路的卒中发生率低于 MS,住院时间短于其他所有入路。所有这些发现可能与患者的基础风险因素有关。