Department of Psychiatry, Erenköy Mental Health and Neurology, Training&Research Hospital , İstanbul, Turkey.
Neurocase. 2020 Aug;26(4):248-251. doi: 10.1080/13554794.2020.1786587. Epub 2020 Jun 26.
Wernicke encephalopathy (WE) is a neuropsychiatric condition associated with thiamine deficiency that includes a triad of mental status changes, ophthalmoplegia, and ataxia. Worsening WE may lead to Korsakoff syndrome(KS), in which cognitive impairments such as confabulation and memory deficits and also psychiatric symptoms may occur. Diagnosis of Wernicke-Korsakoff syndrome can be complicated in many cases. We present the case of a prisoner who commenced a hunger strike and developed WE. The preceding factors were associated with his oral intake refusal, which originated from his mental disorder with psychotic content. We discuss the clinical and treatment concerns for this complicated condition.
威尼克脑病(WE)是一种与硫胺素缺乏相关的神经精神疾病,包括精神状态改变、眼肌瘫痪和共济失调三联征。WE 恶化可能导致柯萨可夫综合征(KS),其中可能出现认知障碍,如虚构和记忆缺陷,以及精神症状。在许多情况下,威尼克-柯萨可夫综合征的诊断可能很复杂。我们报告了一例开始绝食并出现 WE 的囚犯病例。先前的因素与他拒绝口服摄入有关,这源于他具有精神病性内容的精神障碍。我们讨论了这种复杂情况的临床和治疗关注点。