Department of Dermatology and Allergy, Danish Anaesthesia Allergy Centre, Allergy Clinic, Copenhagen University Hospital, Gentofte.
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Curr Opin Allergy Clin Immunol. 2020 Aug;20(4):338-345. doi: 10.1097/ACI.0000000000000654.
The purpose of this review is to provide an update on how best to manage the investigation of suspected perioperative hypersensitivity reactions based on recent literature and key publications.
In the past two years, several very important initiatives have been taken in the field of perioperative hypersensitivity. The 6th national audit project in the United Kingdom has provided new knowledge through a series of studies, including a nationwide prospective study, and the European Academy of Allergy and Clinical Immunology has commissioned a position paper with updated recommendations for investigations. Lastly, a large international working group comprising experts in anesthesiology, allergology, and immunology, the International Suspected Perioperative Allergic Reactions group, has published a series of articles providing updates and new insights into several different key areas of perioperative hypersensitivity.
The investigation of perioperative hypersensitivity reactions is highly complex and aims to identify the correct culprit to ensure future avoidance but also to disprove allergy to other suspected culprits, making them available for subsequent anesthesia. To achieve this, close collaboration between anesthesiologists and allergists is called upon to ensure the best possible outcome for the patient.
本文旨在根据最新文献和主要出版物，就如何最好地调查疑似围手术期过敏反应提供最新信息。
在过去两年中，围手术期过敏领域采取了几项非常重要的举措。英国第 6 次全国审计项目通过一系列研究提供了新知识，包括一项全国性前瞻性研究，欧洲过敏与临床免疫学学会委托撰写了一份立场文件，提出了更新的调查建议。最后，一个由麻醉学、过敏学和免疫学专家组成的大型国际工作组，即国际疑似围手术期过敏反应小组，发表了一系列文章，就围手术期过敏的几个不同关键领域提供了最新信息和新见解。
围手术期过敏反应的调查非常复杂，旨在确定正确的罪魁祸首，以确保未来避免，但也需要反驳对其他可疑罪魁祸首的过敏反应，以便为随后的麻醉做好准备。为此，需要麻醉师和过敏专家之间的密切合作，以确保为患者提供最佳结果。
