Obstet Gynecol. 2020 Jul;136(1):226. doi: 10.1097/AOG.0000000000003942.
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease most commonly involving skin, joints, and kidneys. Usually, it presents in women in puberty or early adulthood. This monograph provides an overview of the role of an obstetrician-gynecologist (ob-gyn) in the treatment of SLE patients. An ob-gyn is uniquely placed in the health care continuum throughout the life cycle of a woman. Notably, an ob-gyn often is the first physician to notice SLE-related rash, swollen joints, cytopenias, or proteinuria in a patient and is the first to provide initial management. Obstetrician-gynecologists must be familiar with SLE effects on reproductive issues, such as SLE effects on the choice of birth control, pregnancy outcomes, and the risks of hormone therapy use, as well as the pregnancy effects on the risk of lupus nephritis flares. Human papillomavirus and associated cancer also are of concern in patients with SLE. Providing care to women with SLE is multifaceted; therefore, ob-gyns often will need to liaise with rheumatologists and other specialists.
系统性红斑狼疮（SLE）是一种常见的自身免疫性疾病，主要影响皮肤、关节和肾脏。通常，它发生在青春期或成年早期的女性中。本专论概述了妇产科医生在治疗 SLE 患者中的作用。妇产科医生在女性的整个生命周期中处于医疗保健连续体的独特位置。值得注意的是，妇产科医生通常是第一个注意到与 SLE 相关皮疹、关节肿胀、血细胞减少或蛋白尿的医生，也是第一个提供初步治疗的医生。妇产科医生必须熟悉 SLE 对生殖问题的影响，例如 SLE 对避孕方法的选择、妊娠结局以及激素治疗使用的风险，以及妊娠对狼疮性肾炎发作风险的影响。人乳头瘤病毒及其相关癌症也与 SLE 患者有关。为 SLE 患者提供护理是多方面的；因此，妇产科医生通常需要与风湿病学家和其他专家联系。
