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原发性上尿路印戒细胞癌 1 例报告并文献复习

A case report of primary upper urinary tract signet-ring cell carcinoma and literature review.

机构信息

Department of Urology, Dongguan People's Hospital, Dongguan, 523000, China.

出版信息

BMC Urol. 2020 Jun 26;20(1):75. doi: 10.1186/s12894-020-00645-y.

DOI:10.1186/s12894-020-00645-y
PMID:32590974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7318531/
Abstract

BACKGROUND

Upper tract urothelial carcinoma with pure non-urothelial histology is an exception but variants are present in ~ 25% of cases. Primary upper urinary tract signet -ring cell carcinoma is extremely rare.

CASE PRESENTATION

We report the case of a 65-year-old male diagnosed primary upper urinary tract signet-ring cell carcinoma while underwent percutaneous nephrolithotomy. Radical nephroureterectomy and adjuvant chemotherapy were performed sequentially. The patient is now recovering well with a regular follow-up for more than 1 year.

CONCLUSIONS

The upper urinary tract malignancy often appears as a high grade, high stage tumor and has a uniformly poor prognosis, but a timely multimodal management can bring a good outcome.

摘要

背景

上尿路尿路上皮癌伴纯非尿路上皮组织学表现较为少见，但约 25%的病例存在此类组织学表现。原发性上尿路胃型细胞癌极其罕见。

病例报告

我们报告了一例 65 岁男性患者的病例，该患者因行经皮肾镜碎石术而被诊断为原发性上尿路胃型细胞癌。随后患者接受了根治性肾输尿管切除术和辅助化疗。目前，患者恢复良好，定期随访超过 1 年。

结论

上尿路恶性肿瘤常表现为高级别、高分期肿瘤，预后普遍较差，但及时采用多模式管理可带来良好的结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f852/7318531/09f1d1273099/12894_2020_645_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f852/7318531/ccbcdd36c4e0/12894_2020_645_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f852/7318531/b1250b001b8f/12894_2020_645_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f852/7318531/236063830e03/12894_2020_645_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f852/7318531/09f1d1273099/12894_2020_645_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f852/7318531/ccbcdd36c4e0/12894_2020_645_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f852/7318531/b1250b001b8f/12894_2020_645_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f852/7318531/236063830e03/12894_2020_645_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f852/7318531/09f1d1273099/12894_2020_645_Fig4_HTML.jpg

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