Wang Hayson Chenyu, Wang Yunting, Long Xiao, Wang Xiaojun
Department of Plastic surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Nuffield Department of Surgical Science, University of Oxford, Oxford, UK.
J Cosmet Dermatol. 2021 Feb;20(2):457-459. doi: 10.1111/jocd.13575. Epub 2020 Jul 14.
Mandibular osteomyelitis after filler injection is extremely rare.
We reported a case of mandibular osteomyelitis after hyaluronic acid injection.
A 33-year-old woman received 1 mL hyaluronic acid injection on her chin 1 year ago, after which her chin kept swelling and painful, and gradually ulcerated with pus flowing out. She received antibiotics, debridement procedures, negative pressure wound therapy, and hyperbaric oxygen therapy without symptoms improved. Cone-beam computed tomography scan showed local bone destruction, sequestrum formation, and tissue calcification on the right mandible body. The patient was diagnosed with mandibular osteomyelitis and received local curettage for the removal of necrotized bone.
Literature search found no case reports on mandibular osteomyelitis after filler injection so far.
Minimizing the risk of contamination and infection is strictly required during the filler injection process. Once the patient shows signs of incurable mandibular infection postoperation, clinicians should consider the possibility of osteomyelitis.
填充剂注射后发生下颌骨骨髓炎极为罕见。
我们报告一例透明质酸注射后发生下颌骨骨髓炎的病例。
一名33岁女性1年前在下巴注射了1毫升透明质酸，此后下巴持续肿胀、疼痛，并逐渐溃疡、流脓。她接受了抗生素、清创手术、负压伤口治疗和高压氧治疗，但症状未改善。锥形束计算机断层扫描显示右下颌骨体局部骨质破坏、死骨形成和组织钙化。该患者被诊断为下颌骨骨髓炎，并接受了局部刮除术以清除坏死骨。
文献检索发现目前尚无填充剂注射后发生下颌骨骨髓炎的病例报告。
在填充剂注射过程中严格要求将污染和感染风险降至最低。一旦患者术后出现下颌骨感染无法治愈的迹象，临床医生应考虑骨髓炎的可能性。
