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胸腔内肌肉皮瓣转位术治疗慢性肺曲霉病。

Intrathoracic Muscle Flap Transposition for the Management of Chronic Pulmonary Aspergillosis.

机构信息

Division of Plastic Surgery, Department of Surgery, Mayo Clinic, 200 First Street SW Rochester, MN.

Mayo Clinic Alix School of Medicine, Rochester, Minnesota.

出版信息

J Plast Reconstr Aesthet Surg. 2020 Oct;73(10):1815-1824. doi: 10.1016/j.bjps.2020.05.068. Epub 2020 May 26.

DOI:10.1016/j.bjps.2020.05.068
PMID:32593571
Abstract

BACKGROUND

The management of chronic pulmonary aspergillosis remains a challenge for thoracic and reconstructive surgeons. Different management options have been proposed with no consensus regarding the best treatment modality. The goal of this study is to report our experience with the use of intrathoracic muscle flaps for the management of pulmonary aspergillosis.

METHODS

We retrospectively reviewed all patients who underwent intrathoracic muscle flap transposition for the management of pulmonary aspergillosis between 1990 and 2010. Demographics, surgical characteristics, and treatment outcomes were collected and analyzed.

RESULTS

A total of 39 patients who underwent 48 muscle flaps were identified. The majority were classified as ASA 3 (n=30, 77%) or ASA 4 (n=8, 21%). Serratus anterior was the most common flap used (n=34), followed by latissimus dorsi (n=6) and pectoralis major (n=5). Flap loss was encountered in three (8%) patients (2 partial, 1 total). Bronchopleural fistula and empyema comprised the two most common intrathoracic complications (26%, 29% respectively). Median follow-up was 33 months (range, 0-216). Successful treatment was achieved in 77% of patients, while operative mortality was 23%.

CONCLUSION

The use of intrathoracic muscle flaps can be a helpful adjunct to surgical resection in the treatment of chronic pulmonary aspergillosis with low rates of flap loss.

摘要

背景

慢性肺部曲霉菌病的治疗仍然是胸外科和重建外科医生面临的挑战。已经提出了不同的治疗选择,但对于最佳治疗方式仍没有共识。本研究的目的是报告我们使用胸腔内肌肉瓣治疗肺部曲霉菌病的经验。

方法

我们回顾性分析了 1990 年至 2010 年间接受胸腔内肌肉瓣转位治疗肺部曲霉菌病的所有患者。收集并分析了人口统计学、手术特点和治疗结果。

结果

共确定了 39 例接受 48 个肌肉瓣的患者。大多数患者被归类为 ASA 3(n=30,77%)或 ASA 4(n=8,21%)。最常用的是前锯肌(n=34),其次是背阔肌(n=6)和胸大肌(n=5)。有 3 例(8%)患者发生瓣丢失(2 例部分丢失,1 例完全丢失)。支气管胸膜瘘和脓胸是最常见的两种胸腔内并发症(分别为 26%和 29%)。中位随访时间为 33 个月(范围 0-216 个月)。77%的患者治疗成功,手术死亡率为 23%。

结论

在治疗慢性肺部曲霉菌病时,胸腔内肌肉瓣的使用可以作为手术切除的有益辅助手段,其瓣丢失率较低。

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J Plast Reconstr Aesthet Surg. 2020 Oct;73(10):1815-1824. doi: 10.1016/j.bjps.2020.05.068. Epub 2020 May 26.
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