Raptopoulos V, Davidoff A, Karellas A, Davis M A, Coolbaugh B L, Smith E H
Department of Radiology, University of Massachusetts Medical Center, Worcester 01655.
AJR Am J Roentgenol. 1988 Jun;150(6):1303-6. doi: 10.2214/ajr.150.6.1303.
Visualization of the head of the pancreas by CT was prospectively evaluated in two groups of 100 patients who did not have pancreatic disease. Patients were given either a fat-density oral contrast material (12.5% corn-oil emulsion and metoclopramide) or a conventional high-density oral contrast material (barium suspension or iodinated solution). There was no statistically significant difference in the subjects' tolerance to the two regimens. There was, however, a significant improvement in ability to distinguish the head of the pancreas from the duodenal C-loop when the fat-density contrast material was given. When pancreaticoduodenal discrimination was graded, patients given corn-oil emulsion and metoclopramide received an average score of 0.94, whereas those given the high-density agent received an average score of 0.74, with 1.00 being the highest possible score (p less than .005). These data suggest that for routine CT evaluation of the head of the pancreas, a combination of corn-oil emulsion and metoclopramide may be superior to the conventional high-density oral contrast agents given without metoclopramide.
对两组各100例无胰腺疾病的患者进行前瞻性CT胰腺头部可视化评估。患者分别服用脂肪密度口服造影剂（12.5%玉米油乳剂和甲氧氯普胺）或传统高密度口服造影剂（钡剂悬浮液或碘化溶液）。两组受试者对两种给药方案的耐受性无统计学显著差异。然而，服用脂肪密度造影剂时，区分胰腺头部与十二指肠C袢的能力有显著提高。在对胰十二指肠区分度进行评分时，服用玉米油乳剂和甲氧氯普胺的患者平均得分为0.94，而服用高密度造影剂的患者平均得分为0.74，满分是1.00（p<0.005）。这些数据表明，对于胰腺头部的常规CT评估，玉米油乳剂和甲氧氯普胺联合使用可能优于未加甲氧氯普胺的传统高密度口服造影剂。
