小脑神经细胞瘤对放疗有良好的反应。
Cerebellar Neurocytoma with Excellent Response to Radiotherapy.
机构信息
Department of Neurology, Peking University First Hospital, Beijing, China.
Department of Neurosurgery, Peking University First Hospital, Beijing, China.
出版信息
World Neurosurg. 2020 Sep;141:327-330. doi: 10.1016/j.wneu.2020.06.133. Epub 2020 Jun 25.
BACKGROUND
Extraventricular neurocytoma (EVN) is a rare neurocytoma occurring in the brain parenchyma outside the ventricular system that shares similar biological behaviors and histopathologic characteristics with central neurocytoma. Reports of EVN localized in the brainstem and cerebellum are relatively uncommon. In addition, few cases with radiotherapy as the only treatment have been reported and their outcomes were unclear.
CASE DESCRIPTION
We report a case of pathologically confirmed EVN of the brainstem and cerebellum in a 43-year-old male who presented with unprovoked nausea and dizziness. The patient received radiotherapy only and showed a favorable outcome during the 2-year follow-up period.
CONCLUSIONS
These results suggest that patients with EVN who are treated with radiotherapy without surgery may have a favorable prognosis.
背景
室管膜外神经细胞瘤（EVN）是一种罕见的发生在脑室系统外脑实质内的神经细胞瘤，其具有与中枢神经细胞瘤相似的生物学行为和组织病理学特征。发生在脑干和小脑的 EVN 报道相对较少。此外，仅有放疗作为唯一治疗方法的病例报告较少，其结果尚不清楚。
病例描述
我们报告了一例 43 岁男性患者的脑干和小脑 EVN 病理确诊病例，该患者表现为自发性恶心和头晕。该患者仅接受了放疗，在 2 年的随访期间预后良好。
结论
这些结果表明，接受放疗而未接受手术治疗的 EVN 患者可能具有良好的预后。
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