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表现为小脑室外神经细胞瘤的视觉和听觉幻觉:罕见部位的罕见肿瘤的不常见表现。

Visual and auditory hallucinations revealing cerebellar extraventricular neurocytoma: uncommon presentation for uncommon tumor in uncommon location.

机构信息

Department of Neurosurgery, School of Medicine, University of Tirana, Albania.

出版信息

Gen Hosp Psychiatry. 2013 Nov-Dec;35(6):680.e1-3. doi: 10.1016/j.genhosppsych.2013.03.011. Epub 2013 May 8.

DOI:10.1016/j.genhosppsych.2013.03.011
PMID:24199787
Abstract

OBJECTIVE

Visual and auditory hallucinations in relation to a cerebellar tumor are rarely reported in children. Primary origin of extraventricular neurocytoma (EVN) in the cerebellum is very rare.

CLINICAL PRESENTATION

We report on a case of a cerebellar EVN in a 13-year-old girl with the initial symptoms of psychiatric manifestations for more than 2 months. Magnetic resonance imaging of the brain revealed a patchy enhanced tumor in the paramedian left cerebellar region. No obstructive hydrocephalus was noted.

INTERVENTION

Total surgical removal of the tumor was performed. The tumor was initially diagnosed as an oligodendroglioma. After special immunohistochemical studies, the final definitive diagnosis was an EVN without isocitrate dehydrogenase mutation.

CONCLUSION

EVNs located in the cerebellum are extremely rare. We discuss the clinical symptoms and histological-immunohistochemical features of this rare tumor in that rare location.

摘要

目的

与小脑肿瘤相关的视觉和听觉幻觉在儿童中很少见报道。室管外神经细胞瘤(EVN)在小脑的原发性起源非常罕见。

临床表现

我们报告了一例 13 岁女孩的小脑 EVN,其最初的症状为超过 2 个月的精神表现。脑部磁共振成像显示左侧小脑旁正中区有斑片状增强的肿瘤。没有发现阻塞性脑积水。

干预措施

进行了肿瘤的完全手术切除。肿瘤最初被诊断为少突胶质细胞瘤。经过特殊的免疫组织化学研究,最终明确诊断为无异柠檬酸脱氢酶突变的 EVN。

结论

位于小脑的 EVN 极为罕见。我们讨论了这种罕见部位罕见肿瘤的临床症状和组织学-免疫组织化学特征。

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