种植体周围炎手术治疗后不同特性表面菌斑控制缺失的影响：一项在犬类中的实验研究

Effect of lack of plaque control after the surgical treatment of peri-implantitis at surfaces with different characteristics: an experimental study in dogs.

作者信息

Favero Giovanni, Apaza Alccayhuaman Karol Alí, Silva Erick Ricardo, Bengazi Franco, Urbizo Joaquin, Kotsu Mitsuo, Botticelli Daniele

机构信息

ARDEC Academy, Viale Giovanni Pascoli 67, 47923, Rimini, Italy.

Depto CTBMF e Periodontia, FORP-USP-Faculty of Ribeirão Preto (SP), Ribeirão Preto, Brazil.

出版信息

Oral Maxillofac Surg. 2020 Dec;24(4):431-439. doi: 10.1007/s10006-020-00870-7. Epub 2020 Jun 27.

DOI:10.1007/s10006-020-00870-7

PMID:32594345

Abstract

OBJECTIVE

The aim of the present study was to evaluate the effect of the induction of peri-implantitis and of plaque accumulation on implants with different surface characteristics after the surgical treatment.

MATERIAL AND METHODS

All mandibular premolars and first molars were extracted bilaterally in six dogs. After 3 months, two non-submerged implants were installed, each with either a hydrophilic sandblasted and acid-etched surface stored in saline solution (SLActive) or an acid-etched and modified with calcium ions surface (UnicCa). After 3 months, ligatures were placed in the sulcus around the implants to induce an experimental peri-implantitis and plaque accumulation was allowed. After 3 months, ligatures were removed and, after one more month of plaque accumulation, a surgical treatment was performed using gauzes soaked in saline and irrigations. X-rays were taken at this stage. Plaque control maintenance was established at the control sites, while plaque accumulation was allowed at the test sites (plaque sites). After 5 months, biopsies were obtained. Marginal bone levels were compared between x-rays and histological assessments.

RESULTS

At the time of peri-implantitis treatment, two SLActive implants were lost. At the euthanasia, seven more implants were lost only in the plaque group, one control and six test implants. The calculated mean values of the marginal bone level of the two surfaces at the treatment were 3.65 ± 1.71 mm in the control group, and 3.65 ± 1.76 mm in the plaque group (p = 0.463). The additional marginal bone loss after 5 months from surgical treatment was 0.67 ± 0.67 mm (UnicCa, 0.48 ± 1.06 mm and SLActive, 0.79 ± 2.10 mm) and 3.11 ± 1.38 mm (UnicCa, 2.67 ± 1.87 mm and SLActive, 3.94 ± 2.11 mm) for the control and plaque groups, respectively (p = 0.028).

CONCLUSIONS

The lack of plaque control after the surgical treatment of the peri-implantitis strongly influenced the marginal bone loss.

摘要

目的

本研究旨在评估种植体周围炎的诱导以及菌斑堆积对手术治疗后具有不同表面特性的种植体的影响。

材料与方法

在六只犬双侧拔除所有下颌前磨牙和第一磨牙。3个月后，植入两枚非潜入式种植体，每枚种植体表面分别为亲水喷砂和酸蚀表面并保存在盐溶液中（SLActive）或酸蚀并经钙离子改性表面（UnicCa）。3个月后，在种植体周围龈沟放置结扎丝以诱导实验性种植体周围炎并允许菌斑堆积。3个月后，移除结扎丝，在又经过1个月的菌斑堆积后，使用浸有盐水的纱布进行冲洗并实施手术治疗。在此阶段拍摄X线片。在对照部位建立菌斑控制维持措施，而在测试部位（菌斑部位）允许菌斑堆积。5个月后，获取活检样本。比较X线片和组织学评估之间的边缘骨水平。

结果

在种植体周围炎治疗时，两枚SLActive种植体丢失。在安乐死时，仅在菌斑组又有七枚种植体丢失，一枚对照种植体和六枚测试种植体。治疗时两个表面边缘骨水平的计算平均值在对照组为3.65±1.71mm，在菌斑组为3.65±1.76mm（p = 0.463）。手术治疗后5个月时，对照组和菌斑组额外的边缘骨丢失分别为0.67±0.67mm（UnicCa为0.48±1.06mm，SLActive为0.79±2.10mm）和3.11±1.38mm（UnicCa为2.67±1.87mm，SLActive为3.94±2.11mm）（p = 0.028）。