Department of Gastroenterology and Hepatology, Hepatology Research Unit, Ghent University, 1K12IE, Corneel Heymanslaan 10, B-9000, Ghent, Belgium.
Department of General and Hepatobiliary Surgery, Liver Transplantation Service, Ghent University, Ghent, Belgium.
Obes Surg. 2020 Nov;30(11):4659-4664. doi: 10.1007/s11695-020-04806-8.
Recent studies have indicated that patients with prior bariatric surgery (BS) are at risk for developing alcohol use disorder. We explored patient demographics and impact on liver disease severity in 11 patients with prior BS listed for transplantation due to alcoholic liver disease, and compared these with 177 patients without BS. BS patients were younger with a female predominance and presented with more severe decompensation. The timeframe between diagnosis, listing, and transplantation was significantly shorter in patients with prior BS. The incidence of post-transplant complications and 3-year survival rate was comparable. In conclusion, alcoholic liver disease with rapid decompensation may develop after BS, warranting rapid identification with referral to a transplant center. Attention should be paid to pre-surgery screening for alcohol overuse risk factors.
最近的研究表明，既往接受过减重手术（BS）的患者有发生酒精使用障碍的风险。我们研究了 11 例因酒精性肝病而接受移植的既往 BS 患者的患者人口统计学特征及其对肝病严重程度的影响，并与 177 例无 BS 的患者进行了比较。BS 患者年龄较小，女性居多，且代偿失调更为严重。BS 患者在诊断、列入名单和移植之间的时间间隔明显缩短。移植后的并发症发生率和 3 年生存率相当。总之，BS 后可能迅速出现酒精性肝病失代偿，需要快速识别并转至移植中心。术前应注意筛查酒精滥用的危险因素。
