对布氏大鼠下丘脑神经元中硫醇：蛋白质二硫键氧化还原酶的免疫组织化学分析
Immunohistochemical analysis of thiol: protein disulfide oxidoreductase in hypothalamic neurons of Brattleboro rat.
作者信息
Bernstein H G, Ansorge S, Nováková V, Reiser M, Dorn A
机构信息
Institute of Anatomy, Medical Academy Magdeburg, Czechoslovakia.
出版信息
Endocrinol Exp. 1988 Mar;22(1):41-4.
The immunolocalization of thiol: protein disulfide oxidoreductase (TPO) in CNS of Wistar rats and homozygous Brattleboro rats was investigated by use of monospecific antiserum and Sternberger's unlabelled immunoenzyme technique. It was revealed that TPO is present in hypothalamic neurons belonging to nucleus supraopticus and paraventricularis. The number of immunopositive nerve cells was reduced in Brattleboro rats as compared to Wistar rats. It was concluded that TPO must have tasks in CNS unrelated to the management of vasopressin production and/or processing.
利用单特异性抗血清和斯特恩伯格未标记免疫酶技术，研究了硫醇：蛋白质二硫键氧化还原酶（TPO）在Wistar大鼠和纯合布拉特洛伯大鼠中枢神经系统中的免疫定位。结果显示，TPO存在于视上核和室旁核的下丘脑神经元中。与Wistar大鼠相比，布拉特洛伯大鼠中免疫阳性神经细胞的数量减少。得出的结论是，TPO在中枢神经系统中必定具有与血管加压素产生和/或加工管理无关的任务。
Zotero 插件