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帕金森病患者向痴呆症转变过程中功能能力的直接和间接评估。

Direct and indirect assessment of functional abilities in patients with Parkinson's disease transitioning to dementia.

作者信息

de Oliveira Gisele Saraiva Reis, Bressan Lúcia, Balarini Fernanda, Jesuino E Silva Raquel Silveira, Brito Manuelina Mariana Capellari Macruz, Foss Maria Paula, Santos-Lobato Bruno Lopes, Tumas Vitor

机构信息

Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.

出版信息

Dement Neuropsychol. 2020 Apr-Jun;14(2):171-177. doi: 10.1590/1980-57642020dn14-020011.

DOI:10.1590/1980-57642020dn14-020011
PMID:32595887
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7304267/
Abstract

UNLABELLED

Cognitive impairment is common in patients with Parkinson's disease (PD), and evaluation of functional abilities is crucial for diagnosis of dementia.

OBJECTIVE

We evaluated differences between direct and indirect functional assessment methods to evaluate functional abilities in PD patients.

METHODS

We evaluated 32 patients with PD and suspected mild dementia using direct and indirect assessment methods.

RESULTS

There was a significant difference between the scores of direct and indirect methods of assessment. Patients and close informants usually overestimated their abilities in many ADL. However, all functional assessment tools used in this study had a relatively good accuracy to predict abnormal performance in a global cognitive scale. Patients with normal cognition according to scores in a global cognitive scale may have some functional impairment in ADL. Direct Assessment of Functional Ability (DAFA) scores correlated linearly with scores in global cognitive scales, and especially with scores in the domains of memory and concentration.

CONCLUSION

Patients and close informants usually overestimate their instrumental abilities in ADL. The direct assessment of daily functioning was more reliable than indirect tools to assess functional losses in patients with PD. Finally, some patients with PD but no dementia may present functional losses in ADL.

摘要

未标注

认知障碍在帕金森病(PD)患者中很常见,功能能力评估对痴呆症诊断至关重要。

目的

我们评估了直接和间接功能评估方法在评估PD患者功能能力方面的差异。

方法

我们使用直接和间接评估方法对32例患有PD且疑似轻度痴呆的患者进行了评估。

结果

直接和间接评估方法的得分存在显著差异。患者及其密切信息提供者通常在许多日常生活活动中高估了自己的能力。然而,本研究中使用的所有功能评估工具在预测整体认知量表中的异常表现方面都具有相对较好的准确性。根据整体认知量表得分认知正常的患者在日常生活活动中可能存在一些功能障碍。功能能力直接评估(DAFA)得分与整体认知量表得分呈线性相关,尤其与记忆和注意力领域的得分相关。

结论

患者及其密切信息提供者通常高估他们在日常生活活动中的工具性能力。直接评估日常功能在评估PD患者的功能丧失方面比间接工具更可靠。最后,一些无痴呆的PD患者在日常生活活动中可能存在功能丧失。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/878c/7304267/c2f21a9ec2b9/1980-5764-dn-14-02-0171-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/878c/7304267/c2f21a9ec2b9/1980-5764-dn-14-02-0171-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/878c/7304267/c2f21a9ec2b9/1980-5764-dn-14-02-0171-gf01.jpg

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Evolution of diagnostic criteria and assessments for Parkinson's disease mild cognitive impairment.帕金森病轻度认知障碍诊断标准和评估的演变。
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Mattis dementia rating scale (DRS) normative data for the brazilian middle-age and elderly populations.
原创研究:使用基于表现的功能评估对认知要求较高的日常功能进行纵向评估,突显了帕金森病患者认知和功能能力的异质性轨迹。
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