认知与癫痫：认知筛查测试
Cognition and epilepsy: Cognitive screening test.
作者信息
Tedrus Glória Maria Almeida Souza, Passos Maria Lina Giacomino Almeida, Vargas Letícia Muniz, Menezes Larissa Estela Ferreira Jacó
机构信息
Postgraduate Program in Health Sciences, Pontifical Catholic University of Campinas, Campinas, SP, Brazil.
Undergraduate Student - Faculty of Medicine, Pontifical Catholic University of Campinas, Campinas, SP, Brazil.
出版信息
Dement Neuropsychol. 2020 Apr-Jun;14(2):186-193. doi: 10.1590/1980-57642020dn14-020013.
UNLABELLED
Cognitive deficits often occur in people with epilepsy (PWE). However, in Brazil, PWE might not undergo neurocognitive evaluation due to the low number of validated tests available and lack of multidisciplinary teams in general epilepsy outpatient clinics.
OBJECTIVE
To correlate Brief Cognitive Battery-Edu (BCB-Edu) scores with epilepsy characteristics of 371 PWE.
METHODS
Clinical and cognitive assessment (MMSE, BCB-Edu) of 371 PWE aged >18 years was performed. The clinical aspects of epilepsy were correlated with BCB-Edu data. Cognitive data of PWE were compared against those of 95 healthy individuals (NC), with p-<0.05.
RESULTS
People with epilepsy had lower cognitive performance than individuals in the NC group. Cognitive aspects also differed according to epilepsy characteristics. Predictive factors for impairment in multiple cognitive domains were age and use of more than one antiepileptic drug (logistic regression; R Nagelkerke=0.135).
CONCLUSION
Worse cognitive performance was found in PWE on different domains. There was a relationship between cognitive impairment and the aspects of epilepsy. BCB-Edu proved to be effective as a cognitive assessment screening test for epilepsy in adults.
未标注
认知缺陷在癫痫患者（PWE）中经常出现。然而，在巴西，由于可用的经过验证的测试数量较少，且一般癫痫门诊缺乏多学科团队，PWE可能无法接受神经认知评估。
目的
将简易认知电池-教育版（BCB-Edu）评分与371例PWE的癫痫特征相关联。
方法
对371例年龄大于18岁的PWE进行临床和认知评估（MMSE、BCB-Edu）。将癫痫的临床方面与BCB-Edu数据相关联。将PWE的认知数据与95名健康个体（NC）的认知数据进行比较，p<0.05。
结果
癫痫患者的认知表现低于NC组个体。认知方面也因癫痫特征而异。多个认知领域受损的预测因素是年龄和使用不止一种抗癫痫药物（逻辑回归；R纳格尔克=0.135）。
结论
在不同领域中，PWE的认知表现较差。认知障碍与癫痫方面之间存在关联。BCB-Edu被证明是一种有效的成人癫痫认知评估筛查测试。
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