Unit of Orthodontics and Paediatric Dentistry, Section of Dentistry-Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, Italy.
Center of Biophotonics, Dental School, Federal University of Bahia (UFBA), Salvador, BA, Brazil.
Biomed Res Int. 2020 May 25;2020:7460938. doi: 10.1155/2020/7460938. eCollection 2020.
The aim of this study was to investigate the effect of Photobiomodulation (PBM) in managing orthodontic pain intensity over time in patients requiring band application on upper first molars.
Maxillary first molars were banded. In the trial group, each molar received single-session PBM on two buccal and two palatal points ( = 830 ± 10 nm; 150 mW, 7.5 J/cm; spot of 0.1 cm; 5 sec per point), while the control group received a placebo treatment. All patients were asked to answer five pain rating scales to assess pain intensity at 5 minutes and 1, 12, 24, and 72 hours and completed a survey describing the type of pain and its temporal course in the next 7 days.
26 patients (mean age 11.8 years) were randomly assigned to a control or a trial group. The trial group showed significantly lower pain intensities ( < 0.05) at 5 min ( = 0.92, SD = 1.32), 1 h ( = 0.77, SD = 1.01), and 12 h ( = 0.77, SD = 1.54) after band application compared to the control group (5 min: = 1.62, SD = 1.26; 1 h: = 1.77, SD = 1.92; and 12 h: = 1.77, SD = 2.17), whereas no difference between groups ( > 0.05) was found at 24 h (trial: = 0.62, SD = 1.71; control: = 1.08, SD = 1.75) and 72 h (trial: = 0.31, SD = 0.75; control: = 0.15, SD = 0.55). Patients in the control group reported more frequently the presence of "compressive pain" (58.8%, < 0.05) from the appliance during the week after the application, while the trial group showed higher frequency of "no pain" (46.2%, < 0.05). However, PBM did not affect the pain onset (trial: = 10.86, SD = 26.97; control: = 5.25, SD = 7.86), peak (trial: = 15.86, SD = 26.29; control: 6.17, SD = 7.96), and end time (trial: 39.57, SD = 31.33; control: = 22.02, SD = 25.42) reported by the two groups ( > 0.05).
PBM might be considered a promising alternative to decrease general pain intensity, although not affecting the typical pain cycle, in terms of the onset, peak, and ending times.
本研究旨在探讨光生物调节（PBM）对上颌第一磨牙带环应用过程中患者正畸疼痛强度随时间的影响。
上颌第一磨牙带环。试验组每颗磨牙在颊侧和腭侧的两个点接受单次 PBM 治疗（=830±10nm；150mW，7.5J/cm；光斑为 0.1cm；每个点 5 秒），而对照组接受安慰剂治疗。所有患者均被要求回答五个疼痛评分量表，以评估 5 分钟和 1、12、24 和 72 小时的疼痛强度，并在接下来的 7 天内完成描述疼痛类型和时间进程的调查问卷。
26 名患者（平均年龄 11.8 岁）被随机分配到对照组或试验组。试验组在带环应用后 5 分钟（=0.92，SD=1.32）、1 小时（=0.77，SD=1.01）和 12 小时（=0.77，SD=1.54）时疼痛强度明显低于对照组（5 分钟：=1.62，SD=1.26；1 小时：=1.77，SD=1.92；12 小时：=1.77，SD=2.17），而两组在 24 小时（试验组：=0.62，SD=1.71；对照组：=1.08，SD=1.75）和 72 小时（试验组：=0.31，SD=0.75；对照组：=0.15，SD=0.55）时无差异（>0.05）。对照组患者在应用后一周内报告更多的“压迫性疼痛”（58.8%，<0.05），而试验组报告更多的“无痛”（46.2%，<0.05）。然而，PBM 并未影响两组疼痛发作（试验组：=10.86，SD=26.97；对照组：=5.25，SD=7.86）、峰值（试验组：=15.86，SD=26.29；对照组：=6.17，SD=7.96）和结束时间（试验组：39.57，SD=31.33；对照组：=22.02，SD=25.42）（>0.05）。
PBM 可能被认为是一种有前途的替代方法，可以降低一般疼痛强度，尽管不影响典型的疼痛周期，就发作、峰值和结束时间而言。
