Król-Turmińska Katarzyna, Olender Alina, Bogut Agnieszka
Medical University of Lublin, Department of Medical Microbiology, Chodźki 1, 20-093 Lublin, Poland.
New Microbiol. 2020 Jul;43(3):103-106. Epub 2020 Jun 29.
Moraxella catarrhalis is considered an important, exclusively human respiratory tract pathogen which, along with Streptococcus pneumoniae and Haemophilus influenzae, is classified as one of the most frequent bacterial etiological factors causing upper respiratory tract infections. In this manuscript, we report the existence of five tetracycline-resistant M. catarrhalis strains with confirmed presence of tetracycline resistance tetB gene. The strains were isolated from children under the age of three with signs of upper respiratory tract infections. Our research also investigated the occurrence of virulence genes in these strains and involved the analysis of drug resistance to five antibiotic groups. It is the first description of clinical strains with confirmed presence of drug resistance tetB genes isolated in Europe.
卡他莫拉菌被认为是一种重要的、仅感染人类呼吸道的病原体，它与肺炎链球菌和流感嗜血杆菌一起，被列为引起上呼吸道感染最常见的细菌病因之一。在本论文中，我们报告了五株对四环素耐药的卡他莫拉菌菌株，已证实其存在四环素耐药tetB基因。这些菌株是从患有上呼吸道感染症状的三岁以下儿童中分离出来的。我们的研究还调查了这些菌株中致病基因的出现情况，并涉及对五个抗生素组的耐药性分析。这是欧洲首次对已证实存在耐药tetB基因的临床菌株进行描述。
