肌肉有氧能力与全身最大摄氧量的关系。

Association between muscle aerobic capacity and whole-body peak oxygen uptake.

机构信息

School of Kinesiology and Nutritional Sciences, California State University of Los Angeles, 5151 University Drive, Los Angeles, CA, 90032, USA.

Department of Biological Sciences, California State University of Los Angeles, Los Angeles, CA, 90032, USA.

出版信息

Eur J Appl Physiol. 2020 Sep;120(9):2029-2036. doi: 10.1007/s00421-020-04402-9. Epub 2020 Jun 28.

DOI:10.1007/s00421-020-04402-9

PMID:32596752

Abstract

PURPOSE

Decline in skeletal muscle mitochondrial oxidative capacity (MOC) is associated with reduced aerobic capacity and increased risk of cardiovascular and metabolic disease. Measuring skeletal muscle MOC may be an alternative method to assess aerobic capacity, especially for individuals unable to perform a whole-body maximum oxygen uptake protocol. In this study, linear regression analysis in two leg muscles was performed to determine whether MOC values could be used to predict whole-body peak oxygen uptake.

METHODS

MOC was measured with near infrared spectroscopy (NIRS) in the medial gastrocnemius (MG) and vastus lateralis (VL) muscles of 26 participants (age, 27.1 ± 5.8 years old). Whole-body peak oxygen uptake (VO peak) was determined by indirect calorimetry during a continuous ramp protocol on a cycle ergometer.

RESULTS

VO peak values were significantly correlated with the muscle recovery rate constant (k) of the MG (kMG, r = 0.59; p < 0.01) and VL (kVL, r = 0.63; p < 0.01) muscles. Summing recovery rate constants of both muscles together (kMG + kVL) improved the strength of the correlation with VO peak (r = 0.78; p < 0.0001) and could explain a majority of the variance (R = 0.61) between the two measurements.

CONCLUSION

Data suggest that NIRS can provide reliable MOC measurements on two leg muscles that correlate well with whole-body peak oxygen uptake.

摘要

目的

骨骼肌线粒体氧化能力（MOC）的下降与有氧能力的降低以及心血管和代谢疾病的风险增加有关。测量骨骼肌 MOC 可能是评估有氧能力的替代方法，特别是对于无法进行全身最大摄氧量方案的个体。在这项研究中，对两条腿的肌肉进行了线性回归分析，以确定 MOC 值是否可用于预测全身峰值摄氧量。

方法

使用近红外光谱（NIRS）在 26 名参与者的内侧腓肠肌（MG）和股外侧肌（VL）中测量 MOC（年龄，27.1±5.8 岁）。全身峰值摄氧量（VO peak）通过在自行车测功计上进行连续斜坡方案的间接热量测定法确定。

结果

VO peak 值与 MG（kMG，r=0.59；p<0.01）和 VL（kVL，r=0.63；p<0.01）肌肉的肌肉恢复速率常数（k）显着相关。将两条肌肉的恢复速率常数相加（kMG+kVL）可提高与 VO peak 的相关性强度（r=0.78；p<0.0001），并可解释两种测量之间的大部分差异（R=0.61）。