Guiyang Judicial Expertise Center of Public Security, Guiyang, Guizhou, China.
Department of Forensic Medicine, Guizhou Medical University, Guiyang, Guizhou, China.
Ann Hum Biol. 2020 Sep;47(6):541-548. doi: 10.1080/03014460.2020.1788159. Epub 2020 Jul 9.
Y-chromosomal short tandem repeats (Y-STRs) are widely used in paternity identification, pedigree investigation, and human population genetic history.
To investigate the Y-STR polymorphisms in a typical Miao population, and explore the genetic differentiation between the Miao population and reference groups.
We detected 36 Y-STRs genotyping in 455 unrelated Miao individuals from Guizhou province, and analysed genetic differentiation between the Miao population and 76 reference groups.
A total of 369 alleles were obtained, and the allele frequencies ranged from 0.0022 to 0.9802. In addition, the haplotype diversity, random match probability, and discrimination capacity values were 0.99997, 0.0022, and 0.9934, respectively. Moreover, the genetic relationships between Guizhou Miao and 76 ethnic populations showed that the population stratification was almost consistent with geographic distribution and language-family.
The 36 Y-STR loci in this study have good polymorphism distributions in the Guizhou Miao population, and therefore would be a useful tool in forensic identification and male parentage testing and even pedigree investigation.
Y 染色体短串联重复序列（Y-STRs）广泛应用于亲子鉴定、谱系调查和人类群体遗传史研究。
调查典型苗族人群中的 Y-STR 多态性，并探讨苗族人群与参照群体之间的遗传分化。
我们对来自贵州省的 455 名无关苗族个体进行了 36 个 Y-STR 基因分型检测，并分析了苗族人群与 76 个参照群体之间的遗传分化。
共获得 369 个等位基因，等位基因频率范围为 0.0022 至 0.9802。此外，单倍型多样性、随机匹配概率和鉴别能力值分别为 0.99997、0.0022 和 0.9934。此外，贵州苗族与 76 个人群的遗传关系表明，群体分层与地理分布和语言家族几乎一致。
本研究中的 36 个 Y-STR 位点在贵州苗族人群中具有良好的多态性分布，因此将成为法医学鉴定、男性亲子鉴定甚至谱系调查的有用工具。
