Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, #07-01, Singapore 138669, Singapore.
J Mater Chem B. 2020 Aug 5;8(30):6317-6321. doi: 10.1039/d0tb01241f.
Antibiotic resistance has become one of the major, deadly threats to public health worldwide. This paper highlights several recent works, which may initiate the development of comprehensive approaches to mitigate antibiotic resistance. The new strategies demonstrate efficiency and efficacy, with very little probability of inducing drug resistance, paving the way for further breakthroughs in drug discovery for infection control.
抗生素耐药性已成为全球公共卫生面临的主要致命威胁之一。本文重点介绍了几项近期的研究工作,这些工作可能为制定综合措施来减轻抗生素耐药性提供了思路。这些新策略显示出了效率和效果,诱导耐药性的可能性很小,为进一步在抗感染药物研发方面取得突破铺平了道路。