van Albada-Kuipers G A, Linthorst J, Peeters E A, Breedveld F C, Dijkmans B A, Hermans J, Vandenbroucke J P, Cats A
Department of Rheumatology, University Hospital Leiden, The Netherlands.
Arthritis Rheum. 1988 May;31(5):667-71. doi: 10.1002/art.1780310513.
We compared the frequencies and types of infections that occurred in 448 patients with rheumatoid arthritis (RA) versus those occurring in 185 control patients who had osteoarthritis or soft tissue rheumatism. At least 1 infection developed in 23% of the RA patients and in 27% of the control patients. Using a series of risk factors, we found no substantial difference in the risk of infection in RA patients compared with that in control patients. Some of these factors, such as being female, having poor functional capacity, and receiving glucocorticoid treatment, were associated with different levels of risk for infection, but the levels were similar in RA patients and control patients.
我们比较了448例类风湿性关节炎（RA）患者与185例骨关节炎或软组织风湿病对照患者发生感染的频率和类型。至少1次感染发生在23%的RA患者和27%的对照患者中。通过一系列风险因素，我们发现RA患者与对照患者相比，感染风险没有实质性差异。其中一些因素，如女性、功能能力差和接受糖皮质激素治疗，与不同程度的感染风险相关，但RA患者和对照患者中的风险水平相似。
