Chicago Medical School at Rosalind Franklin University of Medicine and Science, North Chicago, IL, United States.
Division of Ophthalmology, NorthShore University Health System, 2050 Pfingsten Rd., Ste. 280, Glenview, IL 60026, United States; Department of Ophthalmology and Visual Science, University of Chicago, Chicago, IL, United States.
Dis Mon. 2020 Oct;66(10):101046. doi: 10.1016/j.disamonth.2020.101046. Epub 2020 Jun 27.
The periocular region sees high rates of cancer compared to the rest of the body and can be affected by several unique tumors. Treatment typically involves surgical excision, although adjunctive therapies and prognosis vary depending on the diagnosis. Basal cell carcinoma (BCC) is the most common malignancy affecting this region and should be excised promptly. This is followed by squamous cell carcinoma, which is often mistaken for BCC but is treated similarly. Melanoma is less common but more deadly, with relatively high rates of metastasis and death. Rare tumors that may be found in this region include sebaceous carcinoma, Merkel cell carcinoma, and microcystic adnexal carcinoma. While uncommon, these tumors are associated with poor outcomes and frequent recurrence. Recognition of periocular skin cancer is an important skill for primary care physicians, as prompt diagnosis and treatment can be sight or life-saving.
与身体其他部位相比，眼周区域的癌症发病率较高，并且可能受到几种独特肿瘤的影响。治疗通常涉及手术切除，尽管辅助治疗和预后因诊断而异。基底细胞癌（BCC）是影响该区域最常见的恶性肿瘤，应迅速切除。其次是鳞状细胞癌，它常被误诊为 BCC，但治疗方法相似。黑色素瘤则较为少见，但更致命，转移和死亡的相对比率较高。在这个区域可能发现的罕见肿瘤包括皮脂腺癌、默克尔细胞癌和微囊性附件癌。虽然不常见，但这些肿瘤与不良预后和频繁复发有关。识别眼周皮肤癌是初级保健医生的一项重要技能，因为及时诊断和治疗可以挽救视力或生命。
