Department of Ophthalmology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Eye (Lond). 2013 Feb;27(2):199-207. doi: 10.1038/eye.2012.243. Epub 2012 Nov 30.
It is estimated that 5-10% of all cutaneous malignancies involve the periocular region and management of periocular skin cancers account for a significant proportion of the oculoplastic surgeon's workload. Epithelial tumours are most frequently encountered, including basal cell carcinoma, squamous cell carcinoma, and sebaceous gland carcinoma, in decreasing order of frequency. Non-epithelial tumours, such as cutaneous melanoma and Merkel cell carcinoma, rarely involve the ocular adnexae. Although non-surgical treatments for periocular malignancies are gaining in popularity, surgery remains the main treatment modality and has as its main aims tumour clearance, restoration of the eyelid function, protection of the ocular surface, and achieving a good cosmetic outcome. The purpose of this article is to review the management of malignant periocular tumours, with particular emphasis on surgical management.
据估计，所有皮肤恶性肿瘤中有 5-10%涉及眼周区域，眼周皮肤癌的治疗占眼科整形医生工作量的很大一部分。上皮肿瘤最常发生，包括基底细胞癌、鳞状细胞癌和皮脂腺癌，其频率依次降低。非上皮肿瘤，如皮肤黑色素瘤和 Merkel 细胞癌，很少涉及眼部附属器。尽管眼周恶性肿瘤的非手术治疗越来越受欢迎，但手术仍然是主要的治疗方式，其主要目的是清除肿瘤、恢复眼睑功能、保护眼表面和获得良好的美容效果。本文旨在回顾恶性眼周肿瘤的治疗，特别强调手术治疗。
