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挽救感染的乳房植入物:80 例连续病例的回顾性系列研究结果。

Salvaging the infected breast implant: results of a retrospective series of 80 consecutive cases.

机构信息

L'Institut du Sein-The Paris Breast Centre, Paris, FRANCE.

L'Institut du Sein-The Paris Breast Centre, Paris, FRANCE; Department of Surgery, Wellington Hospital, Wellington, NEW ZEALAND.

出版信息

J Plast Reconstr Aesthet Surg. 2020 Dec;73(12):2232-2238. doi: 10.1016/j.bjps.2020.05.042. Epub 2020 May 25.

Abstract

BACKGROUND

Breast implants are widely used in reconstruction after breast cancer. Infection after implant reconstruction is a major complication, with rates ranging from 5 to 30%. This rate is less for pure cosmetic augmentation. Historically, infection of an implant mandated implant removal for sepsis control. An alternative is to attempt to salvage the infected implant. This path can be a long one, requiring surgery for washouts and prolonged antibiotic therapy. This article documents our experience of infected implant salvage over the last 13 years.

METHODS

We conducted a retrospective analysis of all patients who developed a breast implant infection between January 2005 and January 2018. All patients had both clinical signs of infection and a positive bacteriological sample. Patients were divided into two groups: upfront medical therapy (including those requiring secondary surgical salvage) and primary surgery. The salvage procedure was defined as successful when the implant was still in place three months after the initial reconstruction.

RESULTS

Eighty patients were included: 77 in the medical group and 3 in the surgical group. Overall, implant salvage was achieved in 88.8% of women (n=71). Of these, 73.8% (n=59) underwent medical treatment alone and 15% (n=12) underwent medical treatment followed by surgical management. The main causative organism was staphylococcus in 81.2%. When the infection was caused by a coagulase-negative staphylococcus, the rate of success was 98% (p<0.003).

CONCLUSIONS

This case series reports that salvage of an infected breast implant was achievable in up to 90% of women presenting with a documented infection, the majority requiring antibiotic management only. Early intervention is central to success.

摘要

背景

乳房植入物在乳腺癌重建后被广泛使用。植入物重建后的感染是一个主要的并发症,发生率为 5%至 30%。对于单纯美容性隆乳,这个比例较低。从历史上看,为了控制败血症,感染的植入物必须取出。另一种选择是尝试挽救受感染的植入物。这条道路可能很漫长,需要进行冲洗和长期的抗生素治疗。本文记录了我们过去 13 年中感染的植入物挽救经验。

方法

我们对 2005 年 1 月至 2018 年 1 月期间发生乳房植入物感染的所有患者进行了回顾性分析。所有患者均有感染的临床体征和阳性细菌学样本。患者分为两组:立即进行药物治疗(包括需要二次手术挽救的患者)和初次手术。如果在初始重建后三个月内植入物仍保留,则将挽救程序定义为成功。

结果

共纳入 80 例患者:药物组 77 例,手术组 3 例。总体而言,88.8%(n=71)的女性实现了植入物挽救。其中,73.8%(n=59)仅接受药物治疗,15%(n=12)接受药物治疗后再进行手术管理。主要病原体为葡萄球菌,占 81.2%。当感染由凝固酶阴性葡萄球菌引起时,成功率为 98%(p<0.003)。

结论

本病例系列报告显示,对于有记录感染的女性,多达 90%可以实现感染的乳房植入物挽救,其中大多数仅需要抗生素管理。早期干预是成功的关键。

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