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晚期卵巢癌化疗敏感性测量工具

Measurement Tool of Chemotherapy Sensitivity in Advanced Ovarian Cancer.

作者信息

May Taymaa, Oza Amit M

机构信息

Division of Gynecologic Oncology, Department of Surgical Oncology, Princess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.

Department of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada.

出版信息

Clin Cancer Res. 2020 Sep 1;26(17):4432-4434. doi: 10.1158/1078-0432.CCR-20-1376. Epub 2020 Jun 29.

DOI:10.1158/1078-0432.CCR-20-1376
PMID:32601078
Abstract

The modeled Ca125 ELIMination rate constant K (KELIM) can be used as a measure of chemotherapy sensitivity in women with newly diagnosed advanced epithelial ovarian cancer who are being treated with neoadjuvant chemotherapy. This marker may aid in decision-making regarding surgical resection and alternate systemic treatments in this cohort..

摘要

建模的Ca125清除率常数K(KELIM)可作为新诊断的晚期上皮性卵巢癌女性患者接受新辅助化疗时化疗敏感性的一种衡量指标。该标志物可能有助于该队列患者在手术切除和替代全身治疗方面的决策。

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Measurement Tool of Chemotherapy Sensitivity in Advanced Ovarian Cancer.晚期卵巢癌化疗敏感性测量工具
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A preoperative low cancer antigen 125 level (≤25.8 mg/dl) is a useful criterion to determine the optimal timing of interval debulking surgery following neoadjuvant chemotherapy in epithelial ovarian cancer.术前低癌抗原125水平(≤25.8毫克/分升)是确定上皮性卵巢癌新辅助化疗后间歇性肿瘤细胞减灭术最佳时机的有用标准。
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Neoadjuvant chemotherapy before definite operative approach for women with advanced-stage epithelial ovarian cancer.晚期上皮性卵巢癌女性在确定手术方案前进行新辅助化疗。
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引用本文的文献

1
CA-125 elimination rate constant K (KELIM) as a promising predictor of complete cytoreduction after neoadjuvant chemotherapy in advanced ovarian cancer patients: a retrospective study from two Chinese hospitals.CA-125 消除率常数 K(KELIM)作为新辅助化疗后晚期卵巢癌患者完全肿瘤细胞减灭术的有前途的预测指标:来自两家中国医院的回顾性研究。
BMC Cancer. 2024 May 20;24(1):609. doi: 10.1186/s12885-024-12252-3.
2
Analysis of Autophagy-Related Signatures Identified Two Distinct Subtypes for Evaluating the Tumor Immune Microenvironment and Predicting Prognosis in Ovarian Cancer.自噬相关特征分析确定了两种不同亚型,用于评估卵巢癌的肿瘤免疫微环境和预测预后。
Front Oncol. 2021 May 10;11:616133. doi: 10.3389/fonc.2021.616133. eCollection 2021.