Sedrani S H
Department of Biochemistry, King Saud University, Riyadh, Saudi Arabia.
Eur J Clin Nutr. 1988 Mar;42(3):243-8.
The vitamin D nutritional status and the plasma concentrations of IgG, IgA, IgM and total immunoglobulins were determined in 2052 Saudi subjects. It was observed that females had significantly lower 25-hydroxyvitamin D levels than males and children had lower levels than adults. The mean levels of IgG and IgM were significantly higher in females than in males and those in adults higher than in children. There was a highly significant positive correlation between the concentrations of the circulating form of vitamin D, 25-OHD, and IgG levels in the overall population, in children and in adults. When these groups were classified into males and females the correlation was significant only for females. The significance and importance of this correlation between vitamin D nutritional status and IgG is as yet unknown. The possible clinical relevance of this study's findings are discussed.
对2052名沙特受试者的维生素D营养状况以及IgG、IgA、IgM和总免疫球蛋白的血浆浓度进行了测定。结果发现，女性的25-羟维生素D水平显著低于男性，儿童的水平低于成年人。女性的IgG和IgM平均水平显著高于男性，成年人的水平高于儿童。在总体人群、儿童和成年人中，循环形式的维生素D（25-OHD）浓度与IgG水平之间存在高度显著的正相关。当将这些组分为男性和女性时，这种相关性仅在女性中显著。维生素D营养状况与IgG之间这种相关性的意义和重要性尚不清楚。本文讨论了该研究结果可能的临床相关性。
