Singh Bhupesh, Sharma Sourabh, Bharti Neha, Singh Amrita, Dadia Suchit, Bharti Sudhank
Bharti Eye Foundation and Hospital, New Delhi, India.
Int Ophthalmol. 2020 Nov;40(11):2827-2834. doi: 10.1007/s10792-020-01466-6. Epub 2020 Jun 29.
To evaluate the outcomes of laser corneal surgery and phakic IOL surgery in adult amblyopic eyes.
Retrospective assessment was done in 688 amblyopic eyes 640 patients who underwent LASIK or phakic IOLs. Ophthalmological evaluation included measurement of uncorrected (UDVA) and corrected (CDVA) distance visual acuities. Analysis of modulation transfer function (MTF) was also done post-operatively as a measure of contrast sensitivity. Patients completed follow-up examinations at 1 day, 3 day, 3 months and 12 months after surgery.
The mean patient age was 24.30 ± 3.04 years with 59% females. The CDVA of amblyopic eyes improved significantly from the mean preoperative level of 0.48 ± 0.18 to 0.59 ± 0.18 at 12 months. There was improvement in the contrast sensitivity at all spatial frequencies. Refractive errors were corrected in both LASIK and phakic IOL group, but there was no clinically significant difference in visual outcomes between each group.
Laser vision correction and phakic IOL surgery for amblyopic eyes are promising alternative methods for improving visual outcomes in adult refractive amblyopia patients who have failed with conventional approaches.
评估成人弱视眼行激光角膜手术和有晶状体眼人工晶状体植入手术的效果。
对640例接受准分子激光原位角膜磨镶术(LASIK)或有晶状体眼人工晶状体植入术的688只弱视眼进行回顾性评估。眼科评估包括测量未矫正远视力(UDVA)和矫正远视力(CDVA)。术后还进行调制传递函数(MTF)分析以测量对比敏感度。患者在术后1天、3天、3个月和12个月完成随访检查。
患者平均年龄为24.30±3.04岁,女性占59%。弱视眼的矫正远视力从术前平均水平0.48±0.18显著提高到12个月时的0.59±0.18。所有空间频率的对比敏感度均有所提高。LASIK组和有晶状体眼人工晶状体植入组的屈光不正均得到矫正,但两组间视觉效果无临床显著差异。
对于传统方法治疗失败的成人屈光性弱视患者,激光视力矫正和有晶状体眼人工晶状体植入手术是改善视觉效果的有前景的替代方法。