Mortazavi Hamed, Ghasemi Azadeh, Vatankhah Mohammad Reza
Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Dental private office, Tehran, Iran.
Dent Med Probl. 2020 Apr-Jun;57(2):145-148. doi: 10.17219/dmp/114440.
Cigarette smoking is a major global health problem, associated with various oral diseases, such as oral cancers. Salivary antioxidants may play an important role in fighting against radicals and the oxidative components of cigarettes, which can cause DNA damage. Furthermore, psychological stress, which occurs more often in individuals with type A personality, affects plasma antioxidant levels.
The objective of this study was to compare the levels of salivary total antioxidant capacity (TAC) between smokers and non-smokers according to their personality types.
In this descriptive cross-sectional study, saliva samples were collected from 40 male smokers (with ≥0.1 pack-years) and 40 male non-smokers. After centrifugation, the samples were assessed using an enzyme-linked immunosorbent assay (ELISA) kit. Pearson's correlation, Welch's t-test and the one-way analysis of variance (ANOVA) test were used for statistical analyses.
The TAC of saliva in smokers was significantly lower than in non-smokers (p = 0.019). Type A and type B smokers showed no significant decrease in TAC (p > 0.05 and p = 0.05, respectively) as compared to type A and type B non-smokers, respectively. Type A smokers reported a higher number of cigarettes smoked per day as compared to smokers with type B personality (p = 0.043).
Smoking cigarettes was associated with a significant decrease in salivary TAC. However, the personality type did not affect salivary TAC in the present study.
吸烟是一个全球性的主要健康问题，与多种口腔疾病相关，如口腔癌。唾液中的抗氧化剂可能在对抗自由基和香烟中的氧化成分方面发挥重要作用，这些成分会导致DNA损伤。此外，心理压力在A型人格个体中更常出现，会影响血浆抗氧化剂水平。
本研究的目的是根据人格类型比较吸烟者和非吸烟者唾液总抗氧化能力（TAC）水平。
在这项描述性横断面研究中，从40名男性吸烟者（吸烟量≥0.1包年）和40名男性非吸烟者中采集唾液样本。离心后，使用酶联免疫吸附测定（ELISA）试剂盒对样本进行评估。采用Pearson相关性分析、Welch's t检验和单因素方差分析（ANOVA）进行统计分析。
吸烟者唾液中的TAC显著低于非吸烟者（p = 0.019）。与A型和B型非吸烟者相比，A型和B型吸烟者的TAC没有显著下降（分别为p > 0.05和p = 0.05）。与B型人格吸烟者相比，A型吸烟者报告的每日吸烟量更高（p = 0.043）。
吸烟与唾液TAC显著下降有关。然而，在本研究中人格类型并未影响唾液TAC。
