The Department of Orthopaedics, the Second Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui Province, China.
Centre for Movement and Occupational Rehabilitation Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, UK.
Clin Rehabil. 2020 Dec;34(12):1497-1505. doi: 10.1177/0269215520938852. Epub 2020 Jun 30.
To investigate the effect of small needle-knife therapy in people with painful knee osteoarthritis.
Pilot randomised, controlled trial.
Rehabilitation hospital.
In-patients with osteo-arthritis of the knee.
Either 1 to 3 small needle-knife treatments over seven days or oral Celecoxib. All patients stayed in hospital three weeks, receiving the same mobility-focused rehabilitation.
Oxford Knee Score (OKS), gait speed and kinematics were recorded at baseline, at three weeks (discharge) and at three-months (OKS only). Withdrawal from the study, and adverse events associated with the small needle knife therapy were recorded.
83 patients were randomized: 44 into the control group, of whom 10 were lost by three weeks and 12 at 3 months; 39 into the experimental group of whom eight were lost at three weeks and three months. The mean (SE) OKS scores at baseline were Control 35.86 (1.05), Exp 38.38 (0.99); at three weeks 26.64 (0.97) and 21.94 (1.23); and at three months 25.83 (0.91) and 20.48 (1.14) The mean (SE) gait speed at baseline was 1.07 (0.03) m/sec (Control) and 0.98 (0.03), and at three weeks was 1.14 (0.03) and 1.12 (0.03) ( < 0.05). Linear mixed model statistical analysis showed that the improvements in the experimental group were statistically significant for total OKS score at discharge and three months.
Small needle-knife therapy added to standard therapy for patients with knee osteoarthritis, was acceptable, safe and reduced pain and improved global function on the Oxford Knee Score. Further research is warranted.
探讨小针刀疗法治疗膝骨关节炎疼痛患者的效果。
初步随机对照试验。
康复医院。
膝骨关节炎住院患者。
小针刀治疗 1-3 次（7 天内）或口服塞来昔布。所有患者均住院 3 周，接受相同的以活动能力为重点的康复治疗。
采用牛津膝关节评分（Oxford Knee Score，OKS）、步态速度和运动学评估患者的基线情况、3 周（出院时）和 3 个月（仅评估 OKS）的情况。记录患者退出研究的情况和与小针刀治疗相关的不良事件。
83 例患者随机分组：对照组 44 例，其中 10 例于 3 周时失访，12 例于 3 个月时失访；实验组 39 例，其中 8 例于 3 周时失访，3 例于 3 个月时失访。两组基线时的平均（SE）OKS 评分分别为对照组 35.86（1.05）和实验组 38.38（0.99）；3 周时分别为 26.64（0.97）和 21.94（1.23）；3 个月时分别为 25.83（0.91）和 20.48（1.14）。两组基线时的平均（SE）步态速度分别为对照组 1.07（0.03）m/sec 和实验组 0.98（0.03）m/sec；3 周时分别为 1.14（0.03）m/sec 和 1.12（0.03）m/sec（<0.05）。线性混合模型统计分析显示，实验组在出院时和 3 个月时的 OKS 总分改善具有统计学意义。
小针刀疗法联合膝骨关节炎标准治疗，安全、可接受，可减轻疼痛，改善牛津膝关节评分的整体功能。需要进一步研究。
