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三色发射和双比率半导体聚合物点作为荧光探针，用于体外和体内同时定量测定 Cu 和 pH。

Trichromatic-emission and dual-ratio semiconducting polymer dots as fluorescent probe for simultaneous quantification of Cu and pH in vitro and in vivo.

机构信息

Laboratory of Functionalized Molecular Solids, Ministry of Education, Anhui Key Laboratory of Chemo/Biosensing, Laboratory of Biosensing and Bioimaging (LOBAB), College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241002, P. R. China.

出版信息

Chem Commun (Camb). 2020 Aug 7;56(61):8647-8650. doi: 10.1039/d0cc01811b. Epub 2020 Jun 30.

DOI:10.1039/d0cc01811b
PMID:32602479
Abstract

Novel dual-ratio semiconducting polymer dots (Pdots) with trichromatic-emission in the red, green and blue primary-color regions, are designed as lysosome-targeting nanoprobes for the simultaneous detection and multicolor imaging of pH and Cu in HeLa cells and zebrafish without cross-interference.

摘要

新型双比率半导体聚合物点（Pdots）具有在红色、绿色和蓝色原色区域的三基色发射，被设计为溶酶体靶向纳米探针，用于在 HeLa 细胞和斑马鱼中同时检测和多色成像 pH 和 Cu，而不会发生交叉干扰。

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