Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Clinic for Cardiovascular Surgery, Institute of Cardiovascular Diseases Vojvodina, Sremska Kamenica, Serbia.
Acta Clin Belg. 2022 Feb;77(1):142-146. doi: 10.1080/17843286.2020.1789273. Epub 2020 Jun 30.
Masses inside the heart can cause serious and life-threatening effects to the cardiovascular system, mainly because of hemodynamic obstruction of the blood flow, either in the heart cavities themselves or remotely due to embolization. In this paper, we report a case of left ventricular tumor mass which presented with neurological symptoms due to multiple brain embolism.
A 35-year-old female patient presented with right hemiparesis and dysarthria. Seven days prior to admission she had elevated body temperature and started taking antibiotics. Inflammatory markers were not elevated, and blood cultures were negative. Computerized tomography (CT) and magnetic resonance imaging (MRI) of the brain revealed multiple acute ischemic lesions. Echocardiography showed the presence of a lobular mass inside the left ventricle, which was attached to the basal segment of the lateral left ventricular wall. Based on the laboratory results and additional heart imaging (CT and MRI) the mass was primarily suspected to be a tumor. It was surgically removed. Microscopic analysis of the removed tissue revealed a non-specific endocardial inflammation with formed fresh fibrin thrombi on the surface. During the postoperative recovery intense physical rehabilitation was being performed, so the initial neurological deficit was completely withdrawn.
Intracardiac masses can cause serious and potentially fatal complications that often present with dramatic clinical symptoms. Despite the comprehensive clinical, laboratory, and imaging investigations, intracardiac masses can be hard to distinguish until the definite microscopic analysis. However, with the right approach and multidisciplinary collaboration, they can be successfully managed.
心脏内的肿块会对心血管系统造成严重且危及生命的影响,主要是由于血流的血液动力学阻塞,无论是在心脏腔本身还是由于栓塞而远程发生。在本文中,我们报告了一例左心室肿瘤肿块的病例,该肿块因多发脑栓塞而出现神经系统症状。
一名 35 岁女性患者出现右侧偏瘫和构音障碍。在入院前 7 天,她体温升高并开始服用抗生素。炎症标志物不升高,血培养阴性。脑计算机断层扫描(CT)和磁共振成像(MRI)显示多发性急性缺血性病变。超声心动图显示左心室内部存在一个小叶状肿块,该肿块附着在左心室外侧壁的基底段。根据实验室结果和其他心脏成像(CT 和 MRI),该肿块主要被怀疑为肿瘤。它被手术切除。切除组织的显微镜分析显示,心内膜有非特异性炎症,表面形成新鲜纤维蛋白血栓。在术后恢复期间,进行了强烈的物理康复治疗,因此最初的神经功能缺损完全消失。
心内肿块可引起严重且潜在致命的并发症,这些并发症通常伴有明显的临床症状。尽管进行了全面的临床、实验室和影像学检查,但在进行明确的微观分析之前,心内肿块可能难以区分。然而,通过正确的方法和多学科合作,可以成功地进行管理。